Monoclonal Antibodies and Their Functional Fragments in Research, Diagnosis and Therapy

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Technology: general issues; adoptive immunotherapy; affibody molecules; affinity; aggregation; AL amyloidosis; amyloid; anti-CD38 MoAb; antibody; antibody fragment; antibody fragments; Antibody-Drug Conjugate; antibody-drug conjugates; BCMA; belantamab mafodotin; bispecific; bispecific T-cell engager; blood-brain barrier; cancer therapy; CAR adaptor; CD38; cDNA; CHI3L1; chimeric antigen receptor (CAR T); chimeric antigen receptor T-cells; cross-linking; Daratumumab; developability; drug targeting; E. coli; Fab; glutamate carboxypeptidase II; guinea pig; idecabtagene vicleucel; immunization; immunogenicity; in vivo imaging; Isatuximab; JNJ-68284528; lung metastasis; Mabs; modular CAR T; monoclonal antibodies; monoclonal antibody; myeloma; NAALADase; neurodegenerative disorders; neurotoxicity; non-specific binding; nucleocapsid; NUsc1; oligomer; payload; phage display; pharmacokinetics; polyspecificity; porcine deltacoronavirus; prostate cancer; prostate-specific membrane antigen; protein engineering; protocol; receptor-mediated transcytosis; scFv; self-association; single chain; solubility; specificity; split CAR; stability; transferrin receptor; universal CAR T; universal immune receptor; viscosity; YKL-40
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (278 p.)
• ISBN: 9783036531663; 9783036531670; books978-3-0365-3166-3
• Access: Open Access

This book is a compendium of scientific articles submitted to a Special Issue of International Journal of Molecular Sciences, fostered by MDPI and curated by Dr. Annamaria Sandomenico and Dr. Menotti Ruvo from the Institute of Biostructure and Bioimaging of the National Research Council. All articles underwent a rigorous peer review and were selected to highlight the properties that make monoclonal antibodies and their functional fragments some of the most useful and versatile assets in therapy and diagnosis.