Molecular and Cellular Mechanisms of Preeclampsia

• Format: eBook
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Biology, life sciences; Research & information: general; adipocyte; AGE; angiogenesis; animal models of human disease; asymmetric dimethylarginine; Atg7; autonomic nervous system; autophagy; baroreflex sensitivity; biomarkers; blunted cardiac response; Body mass index (BMI); cardiovascular adaptations; cardiovascular dysfunction; cardiovascular risk; cardiovascular/cerebrovascular diseases; CCL2; cerebral cytokines; chemerin; children; CmklR1; decidua; DNA methylation; echocardiography; endothelial dysfunction; eNOS; eNOS-knockout; epigenetics; erythropoiesis; exosomes; FGR; Gal 10; Gal 13; Gal 14; Gal 16; H19; hematopoietic stem/progenitor cells; highly active anti-retroviral therapy; histone post translational modifications; homocysteine; HOX genes; human immunodeficiency virus; hydroxychloroquine; hypertensive disorders of pregnancy; IL-11; IL-6; immune response; inflammasomes; inflammation; intra-uterine growth restriction; invasion; IUGR; low dose aspirin; low protein diet; LPS; lymphangiogenesis; lysosomes; macrophage; maternal cardiovascular system; metabolism 3; micro-bleeds; microglia; microRNA expression; miR-210; miRNAs; monocyte; n/a; nitric oxide; non coding RNAs; obstetrics 4; p62/SQSTM1; PE; phosphocreatine 2; placenta; placental bioenergetics 1; placental insufficiency; Placental protein 13; placentation; polymorphism; preeclampsia; pregnancy; pregnancy complications; pregnancy outcome; prehypertension/hypertension; primary prevention; protein aggregation; RAGE; RARRES; risk prediction; screening; sEng; sFlt-1; speckle tracking echocardiography; TNF-α; trophoblast; umbilical cord blood; uterine artery; uterine glands; uterine milk; vagal withdrawal
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication

 This Special Issue on the "Molecular and Cellular Mechanisms of Preeclampsia" belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics" of the International Journal of Molecular Sciences. It was a very successful Special Issue as it contains 20 published papers, including one editorial, nine original research papers, and ten reviews on the topic. The original publications cover a wide spectrum of topics, including alterations and involvement of specific factors during preeclampsia, new non-invasive technologies to identify changes, new treatment options, animal models, gender aspects, and effects of the pregnancy pathology later in life. The review publications again cover a wide spectrum of topics, including factors and pathways involved in preeclampsia, effects on the maternal vascular and immune systems, effects on the placenta and the trophoblast, epigenetic changes, new preventive strategies, and new views on the current hypotheses on preeclampsia. Taken together, this Special Issue gives a fantastic overview on a broad spectrum of topics, all of which are important to identify the real etiology of preeclampsia and to finally develop real treatment options.