The Application of Viruses to Biotechnology

• Format: eBook
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Technology: general issues; AAV; adeno-associated virus; adeno-associated virus (AAV) vector; apple latent spherical virus vector; aspect ratio; bacmid; Bacteriophage; baculovirus; biocontrol; bioreactor; breeding of grapevine; cancer; cancer gene therapy; cancers; carotenoid biosynthesis; chemokines; chikungunya virus; circular RNA; clodronate; codon harmonization; codon optimization; comparative genomics; COVID-19; COVID-19 vaccines; CPMV; CRISPR; CRISPR-cas9; CRISPR/Cas systems; CRISPR/Cas9; diagnosis; DNA-based vaccines; enhancer; Escherichia coli; expression vectors; geminivirus; gene editing; gene expression; gene therapy; genome editing; genome stability; grapevine; heterologous expression; hydrothermal vent; Hypnocyclicus thermotrophus; immunization; infectious bursal disease virus; infectious diseases; insect cells; jaagsiekte sheep retrovirus (JSRV); LTR; lytic cassette; macrophage; nanotechnology; Newcastle disease virus; phage diversity; phages; pig; plant genome engineering; plant virus; porcine epidemic diarrhea virus; prevention; prophage; protein expression; PVX; recombinant Lactococcus lactis; reduced generation time; reverse genetics; RNA-based vaccines; Salmonella; SARS-CoV-2; self-replicating RNA vectors; theranostics; TMV; Tn7; transduction; treatment; vaccine; vaccines; variant strain; viral resistance; viral vaccines; viral vector; viral vectors; viroid; virus elimination; virus-induced flowering; virus-induced gene silencing (VIGS); viruses; VLP; VLPs; VNPs
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication

 Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.