Genomics and Models of Nerve Sheath Tumors

Genomics and Models of Nerve Sheath Tumors

Nerve sheath tumors can be a significant cause of morbidity for many patients. These include benign tumors such as schwannomas, diffuse and plexiform neurofibromas, and atypical neurofibromas, as well as the aggressive soft tissue sarcoma known as the malignant peripheral nerve sheath tumor (MPNST)....

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Bibliographic Details
Format:	eBook
Language:	English
Published:	Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
Subjects:	Medicine and Nursing cancer capmatinib chemoprevention clinical genetics COX-2 inhibitor CRISPR/Cas9 doxorubicin genetically engineered mouse models genomics heterogeneity kinase kinome adaptation kinome reprogramming latent variables machine learning malignancy malignant peripheral nerve sheath tumor malignant peripheral nerve sheath tumors mebendazole (MBZ) MEK MET metaVIPER mouse models MPNST nerve sheath tumor nerve sheath tumors neurofibromatosis neurofibromatosis 1 (NF1) neurofibromatosis type 1 neurofibromatosis type 1 syndrome neurofibromin 1 next generation sequencing NF1 pathology plexiform neurofibromas polycomb repressive complex PRC2 random forest sarcoma Schwann cells supervised learning tram transfer learning tumor deconvolution tumor evolution tumor microenvironment
Online Access:	Open Access: DOAB: description of the publication Open Access: DOAB, download the publication

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