Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules

• Format: eBook
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Biology, life sciences; Research & information: general; alginate; alginate gelispheres; anti-tumor; antimicrobial activity; antimicrobial delivery; antitumoral activity; aqueous humor; arsenic trioxide; bio-imaging; bioactive molecules; biofilm; biofunctionalization; biomimetic magnetite; carbon dots; citric acid; coaxial electrospraying; coculture; composite; crosslinked matrices; curcumin; direct emulsification; double coating layer; drug delivery; drug delivery systems; drug skin permeation; Franz cells; HER2; isoniazid; loxoprofen; magnetic hyperthermia; magnetite; MamC; membranes; microfluidics; microparticulate; mixture design; N-hydroxyphthalimide; n/a; nanoemulsion; nanofibers; nanoparticles; nanoparticles stability; pediatric drug delivery; pharmaceutical particulates; pharmacokinetic studies; PLGA discs; pluronic F68; polymer gels; polymer-lipid; polymeric membrane; polymeric nanoparticles; polystyrene µPs; polyvinylpyrrolidone; powder flow properties; process-property-performance relationship; prolonged release; pseudomonas aeruginosa; reconstitutable dry suspension; red blood cells membrane; reduce toxicity; sodium alginate nanoparticles; spreading angle; sustained release pellets; tape stripping; textural analysis; tuberculosis; wound dressing; wound infection
• Online Access: Open Access: DOAB: description of the publication; Open Access: DOAB, download the publication
• Physical Description: 1 online resource (220 p.)
• ISBN: 9783039363926; 9783039363933; books978-3-03936-393-3
• Access: Open Access

This book is a collection of papers published in the Special Issue of Pharmaceutics, entitled "Pharmaceutical Particulates and Membranes for Delivery of Drugs and Bioactive Molecules". A drug release profile is a consequential factor for nanoparticle application, directly related to drug stability and therapeutic results, as well as formulation development. Pharmaceutical particulates of different sizes and shapes (e.g., liposomes, oil-in-water emulsions, polymeric nano- and microspheres, metallic nanoparticles (NPs) such as gold, silver and iron oxide crystals, and core-shell hybrid NPs) offer many diagnostic and therapeutic applications. Membranes are also extensively utilized in many applications. They are especially beneficial to the distribution of macromolecular drugs and biopharmaceutical drugs (peptides, proteins, antibodies, oligonucleotides, plasmids, and viruses) with physicochemical and pharmacokinetic vulnerability. The delivery of drugs and bioactive molecules using particulates and membranes has gained a great deal of attention for various applications, such as the treatment of secondary infections, cancer treatment, skin regeneration, orthopaedic applications, and antimicrobial drug delivery. In addition, several production techniques have been utilized for the fabrication of particulates and membranes in the last decade, which include lyophilisation, micro-emulsion, nano-spray dryer, nano-electrospinning, slip casting and 3D printers. Therefore, pharmaceutical particulates and membranes possess excellent prospects to deliver drugs and bioactive molecules with the potential to improve new delivery strategies like sustained and controlled release.