Personalizing Simulations of the Human Atria : Intracardiac Measurements, Tissue Conductivities, and Cellular Electrophysiology

This work addresses major challenges of heart model personalization. Analysis techniques for clinical intracardiac electrograms determine wave direction and conduction velocity from single beats. Electrophysiological measurements are simulated to validate the models. Uncertainties in tissue conducti...

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Bibliographic Details
Format: eBook
Language:English
Published: KIT Scientific Publishing 2011
Series:Karlsruhe transactions on biomedical engineering / Ed.: Karlsruhe Institute of Technology / Institute of Biomedical Engineering
Subjects:
Online Access:Open Access: DOAB: description of the publication
Open Access: DOAB, download the publication
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720 1 |a Weber, Frank Michael  |4 aut 
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520 |a This work addresses major challenges of heart model personalization. Analysis techniques for clinical intracardiac electrograms determine wave direction and conduction velocity from single beats. Electrophysiological measurements are simulated to validate the models. Uncertainties in tissue conductivities impact on simulated ECGs. A minimal model of cardiac myocytes is adapted to the atria. This makes personalized cardiac models a promising technique to improve treatment of atrial arrhythmias. 
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546 |a English 
650 7 |a Technology: general issues  |2 bicssc 
653 |a Atrial fibrillation 
653 |a Cardiac modelling 
653 |a Electroyphsiology 
653 |a Intracardiac electrograms 
653 |a Model personalization 
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