Microenvironment-Derived Stem Cell Plasticity
Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions,...
| Format: | eBook |
|---|---|
| Language: | English |
| Published: |
Frontiers Media SA
2017
|
| Series: | Frontiers Research Topics
|
| Subjects: | |
| Online Access: | Open Access: DOAB: description of the publication Open Access: DOAB, download the publication |
| LEADER | 02442namaa2200505uu 4500 | ||
|---|---|---|---|
| 001 | doab53417 | ||
| 003 | oapen | ||
| 005 | 20210211 | ||
| 006 | m o d | ||
| 007 | cr|mn|---annan | ||
| 008 | 210211s2017 xx |||||o ||| 0|eng d | ||
| 020 | |a 978-2-88945-344-3 | ||
| 020 | |a 9782889453443 | ||
| 024 | 7 | |a 10.3389/978-2-88945-344-3 |2 doi | |
| 040 | |a oapen |c oapen | ||
| 041 | 0 | |a eng | |
| 042 | |a dc | ||
| 072 | 7 | |a M |2 bicssc | |
| 720 | 1 | |a Marietta Herrmann |4 aut | |
| 720 | 1 | |a Ivana Gadjanski |4 aut | |
| 720 | 1 | |a Jelena Krstic |4 aut | |
| 720 | 1 | |a Slavko Mojsilovic |4 aut | |
| 245 | 0 | 0 | |a Microenvironment-Derived Stem Cell Plasticity |
| 260 | |b Frontiers Media SA |c 2017 | ||
| 300 | |a 1 online resource (114 p.) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Frontiers Research Topics | |
| 506 | 0 | |a Open Access |f Unrestricted online access |2 star | |
| 520 | |a Plasticity is the hallmark of stem cells. At the same time, stem cells, like any other cell type, are influenced by their microenvironment and respond to it accordingly. A specific microenvironment is defined by a variety of factors, including biological and chemical factors, cell-cell interactions, but also metabolic and mechanical cues. Such dynamic and specialized microenvironment where the stem cells reside is considered a stem cell niche. Tissue injury as well as malignant tissue alterations lead to changes in the niche influencing the plasticity and biology of residing stem cells. Similarly, the niche changes upon tissue damage, which eventually induces differentiation of stem cells and ultimately regeneration of the tissue. | ||
| 540 | |a Creative Commons |f https://creativecommons.org/licenses/by/4.0/ |2 cc |u https://creativecommons.org/licenses/by/4.0/ | ||
| 546 | |a English | ||
| 650 | 7 | |a Medicine |2 bicssc | |
| 653 | |a extracellular vesicles (EVs) | ||
| 653 | |a imaging | ||
| 653 | |a immunomodulation | ||
| 653 | |a microenvironment | ||
| 653 | |a oxygen tension | ||
| 653 | |a plasticity | ||
| 653 | |a stem cells | ||
| 653 | |a tissue regeneration | ||
| 793 | 0 | |a DOAB Library. | |
| 856 | 4 | 0 | |u https://directory.doabooks.org/handle/20.500.12854/53417 |7 0 |z Open Access: DOAB: description of the publication |
| 856 | 4 | 0 | |u https://www.frontiersin.org/research-topics/4681/microenvironment-derived-stem-cell-plasticity |7 0 |z Open Access: DOAB, download the publication |