Prophylactic treatment of rapamycin ameliorates naturally developing and episode -induced heterotopic ossification in mice expressing human mutant ACVR1

by Hirotsugu Maekawa, Shunsuke Kawai, Megumi Nishio, Sanae Nagata, Yonghui Jin, Hiroyuki Yoshitomi, Shuichi Matsuda, Junya Toguchida
Published 2020-05-01

SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier.

by Sakura Tamaki, Makoto Fukuta, Kazuya Sekiguchi, Yonghui Jin, Sanae Nagata, Kazuo Hayakawa, Sho Hineno, Takeshi Okamoto, Makoto Watanabe, Knut Woltjen, Makoto Ikeya, Tomohisa Kato, Junya Toguchida
Published 2015-01-01

Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin.

by Akira Nasu, Makoto Ikeya, Takuya Yamamoto, Akira Watanabe, Yonghui Jin, Yoshihisa Matsumoto, Kazuo Hayakawa, Naoki Amano, Shingo Sato, Kenji Osafune, Tomoki Aoyama, Takashi Nakamura, Tomohisa Kato, Junya Toguchida
Published 2013-01-01

Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes.

by Yonghui Jin, Hassan Elalaf, Makoto Watanabe, Sakura Tamaki, Sho Hineno, Kazuhito Matsunaga, Knut Woltjen, Yukiko Kobayashi, Sanae Nagata, Makoto Ikeya, Tomohisa Kato, Takeshi Okamoto, Shuichi Matsuda, Junya Toguchida
Published 2015-01-01