Implications of HIV-1 Nef for “Shock and Kill” Strategies to Eliminate Latent Viral Reservoirs

by Xiaomei T. Kuang, Mark A. Brockman
Published 2018-11-01

19 HIV-1 Nef enhances viral reactivation and downregulates HLA class I: a dual role in modulating immune-mediated clearance of reservoirs

by XiaomeiT Kuang, Steven Jin, TristanM Markle, MarkA Brockman
Published 2017-07-01

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

by Macdonald Mahiti, Mako Toyoda, Xiaofei Jia, Xiaomei T. Kuang, Francis Mwimanzi, Philip Mwimanzi, Bruce D. Walker, Yong Xiong, Zabrina L. Brumme, Mark A. Brockman, Takamasa Ueno
Published 2016-01-01

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity

by Steven W. Jin, Nirmin Alsahafi, Xiaomei T. Kuang, Shayda A. Swann, Mako Toyoda, Heinrich Göttlinger, Bruce D. Walker, Takamasa Ueno, Andrés Finzi, Zabrina L. Brumme, Mark A. Brockman
Published 2019-11-01

No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial.

by Denis R Chopera, Jaclyn K Mann, Philip Mwimanzi, Saleha Omarjee, Xiaomei T Kuang, Nonkululeko Ndabambi, Sarah Goodier, Eric Martin, Vivek Naranbhai, Salim Abdool Karim, Quarraisha Abdool Karim, Zabrina L Brumme, Thumbi Ndung'u, Carolyn Williamson, Mark A Brockman, CAPRISA 004 TRAPS Team
Published 2013-01-01

Genotypic and functional impact of HIV-1 adaptation to its host population during the North American epidemic.

by Laura A Cotton, Xiaomei T Kuang, Anh Q Le, Jonathan M Carlson, Benjamin Chan, Denis R Chopera, Chanson J Brumme, Tristan J Markle, Eric Martin, Aniqa Shahid, Gursev Anmole, Philip Mwimanzi, Pauline Nassab, Kali A Penney, Manal A Rahman, M-J Milloy, Martin T Schechter, Martin Markowitz, Mary Carrington, Bruce D Walker, Theresa Wagner, Susan Buchbinder, Jonathan Fuchs, Beryl Koblin, Kenneth H Mayer, P Richard Harrigan, Mark A Brockman, Art F Y Poon, Zabrina L Brumme
Published 2014-04-01