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John Howard Wallace
| birth_place = Cincinnati, Ohio, U.S.
| death_date =
| nationality = American
| workplaces = Harvard University, Tulane University, Ohio State University, University of Louisville
| alma_mater = Howard University, Ohio State University
| thesis_title = A Serologic Study of Virus Modified Erythrocytes
| thesis_url = https://www.proquest.com/openview/75ed100e3188c2407eac0b10f5dd4a02/1?pq-origsite=gscholar&cbl=18750&diss=y
| thesis_year = 1953
| doctoral_advisor = Dr. M.C. Dodd
}}
John Howard Wallace (March 8, 1925 – 1992) was an American immunologist and microbiologist.
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