Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders

by Ronald W. Irwin, Christine M. Solinsky, Roberta Diaz Brinton
Published 2014-07-01

Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease

by Ronald W. Irwin, Jun Ming Wang, Shuhua eChen, Roberta Diaz Brinton
Published 2012-01-01

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.

by Shuhua Chen, Jun Ming Wang, Ronald W Irwin, Jia Yao, Lifei Liu, Roberta Diaz Brinton
Published 2011-01-01

GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

by S.K.S. Bengtsson, T. Bäckström, R. Brinton, R.W. Irwin, M. Johansson, J. Sjöstedt, M.D. Wang
Published 2020-05-01

NUP98 – a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer

by Paul B. Mullan, Victoria Bingham, Paula Haddock, Gareth W. Irwin, Elaine Kay, Stephen McQuaid, Niamh E. Buckley
Published 2019-04-01

Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease.

by Ronald W Irwin, Christine M Solinsky, Carlos M Loya, Francesco G Salituro, Kathleen E Rodgers, Gerhard Bauer, Michael A Rogawski, Roberta Diaz Brinton
Published 2015-01-01

A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats.

by Jun Ming Wang, Xu Hou, Samuel Adeosun, Rosanne Hill, Sherry Henry, Ian Paul, Ronald W Irwin, Xiao-Ming Ou, Steven Bigler, Craig Stockmeier, Roberta Diaz Brinton, Elise Gomez-Sanchez
Published 2012-01-01

The brain decade in debate: III. Neurobiology of emotion

by C. Blanchard, R. Blanchard, J.-M. Fellous, F.S. Guimarães, W. Irwin, J.E. LeDoux, J.L. McGaugh, J.B. Rosen, L.C. Schenberg, E. Volchan, C. Da Cunha
Published 2001-03-01

Automated Tumour Recognition and Digital Pathology Scoring Unravels New Role for PD-L1 in Predicting Good Outcome in ER-/HER2+ Breast Cancer

by Matthew P. Humphries, Sean Hynes, Victoria Bingham, Delphine Cougot, Jacqueline James, Farah Patel-Socha, Eileen E. Parkes, Jaine K. Blayney, Michael A. O’Rorke, Gareth W. Irwin, Darragh G. McArt, Richard D. Kennedy, Paul B. Mullan, Stephen McQuaid, Manuel Salto-Tellez, Niamh E. Buckley
Published 2018-01-01

Jaarverslag 1970

by Joseph-John Nevadomsky, Go Gien Tjwan, Clifford Geertz, A.F. Ros, Umar Junus, H. Aveling, Yahya Ismail, R. Roolvink, Anthony Reid, Graham W. Irwin, Fernand Mendes Pinto, John Bastin, A.J. Bernet Kempers, A.H.N. Verwey, F.G. Bailey, S. Arasaratnam, A.F. Marks, G.J. Kruijer
Published 1971-04-01

The NeST (Neoadjuvant systemic therapy in breast cancer) study: National Practice Questionnaire of United Kingdom multi-disciplinary decision making

by I. Whitehead, G. W. Irwin, F. Bannon, C. E. Coles, E. Copson, R. I. Cutress, R. V. Dave, M. D. Gardiner, M. Grayson, C. Holcombe, S. Irshad, C. O’Brien, R. L. O’Connell, C. Palmieri, A. M. Shaaban, N. Sharma, J. K. Singh, S. Potter, S. A. McIntosh, on behalf of the NeST Study Research Collaborative
Published 2021-01-01