Reductive glutamine metabolism is a function of the α-ketoglutarate to citrate ratio in cells

by Fendt, Sarah-Maria, Bell, Eric L., Mayers, Jared R., Vokes, Natalie I., Stephanopoulos, Gregory, Keibler, Mark Andrew, Wasylenko, Thomas Michael, Guarente, Leonard Pershing, Vander Heiden, Matthew G., Olenchock, Benjamin
Published 2014

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

by Lewis, Caroline A, Parker, Seth J, Fiske, Brian Prescott, McCloskey, Douglas, Gui, Dan Yi, Green, Courtney R., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M., Vokes, Natalie I., Lewis, Caroline
Published 2016

Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma

by Liu, David V., Liu, Derek, Jerby-Arnon, Livnat, Vokes, Natalie I., Margolis, Claire A., Conway, Jake, He, Meng Xiao, Elmarakeby, Haitham, Dietlein, Felix, Miao, Diana, Tracy, Adam, Izar, Benjamin, Regev, Aviv, Van Allen, Eliezer M.
Published 2020

Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis

by Locasale, Jason W., Grassian, Alexandra R., Melman, Tamar, Lyssiotis, Costas A., Mattaini, Katherine Ruth, Bass, Adam J., Heffron, Gregory J., Metallo, Christian M., Muranen, Taru, Sharfi, Hadar, Sasaki, Atsuo T., Anastasiou, Dimitrios, Mullarky, Edouard, Vokes, Natalie I., Sasaki, Mika, Beroukhim, Rameen, Stephanopoulos, Gregory, Ligon, Azra H., Meyerson, Matthew L., Richardson, Andrea L., Chin, Lynda, Wagner, Gerhard, Asara, John M., Brugge, Joan S., Cantley, Lewis C., Vander Heiden, Matthew G.
Published 2013