Optimization of trans-Splicing for Huntington's Disease RNA Therapy

by Hansjörg Rindt, Colton M. Tom, Christian L. Lorson, Virginia B. Mattis
Published 2017-10-01

Stimulation of GABA-induced Ca2+ influx enhances maturation of human induced pluripotent stem cell-derived neurons.

by David J Rushton, Virginia B Mattis, Clive N Svendsen, Nicholas D Allen, Paul J Kemp
Published 2013-01-01

Human Huntington’s Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation

by Shagun R. Mehta, Colton M. Tom, Yizhou Wang, Catherine Bresee, David Rushton, Pranav P. Mathkar, Jie Tang, Virginia B. Mattis
Published 2018-10-01

In Vivo Tracking of Human Neural Progenitor Cells in the Rat Brain Using Magnetic Resonance Imaging is Not Enhanced by Ferritin Expression

by Ksenija Bernau, Christina M. Lewis, Anna M. Petelinsek, Matthew S. Reagan, David J. Niles, Virginia B. Mattis, M. Elizabeth Meyerand, Masatoshi Suzuki, Clive N. Svendsen
Published 2016-03-01

Huntington’s Disease Patient-Derived Astrocytes Display Electrophysiological Impairments and Reduced Neuronal Support

by Veronica J. Garcia, David J. Rushton, David J. Rushton, Colton M. Tom, Nicholas D. Allen, Paul J. Kemp, Clive N. Svendsen, Virginia B. Mattis
Published 2019-06-01

The Interaction of Aging and Cellular Stress Contributes to Pathogenesis in Mouse and Human Huntington Disease Neurons

by Emily Machiela, Ritika Jeloka, Nicholas S. Caron, Shagun Mehta, Mandi E. Schmidt, Helen J. E. Baddeley, Colton M. Tom, Nalini Polturi, Yuanyun Xie, Virginia B. Mattis, Michael R. Hayden, Amber L. Southwell, Amber L. Southwell
Published 2020-09-01

The difficulty to model Huntington’s disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells

by Kim Le Cann, Alec Foerster, Corinna Rösseler, Andelain Erickson, Petra Hautvast, Sebastian Giesselmann, Daniel Pensold, Ingo Kurth, Markus Rothermel, Virginia B. Mattis, Geraldine Zimmer-Bensch, Stephan von Hörsten, Bernd Denecke, Tim Clarner, Jannis Meents, Angelika Lampert
Published 2021-03-01