Field-Template, QSAR, Ensemble Molecular Docking, and 3D-RISM Solvation Studies Expose Potential of FDA-Approved Marine Drugs as SARS-CoVID-2 Main Protease Inhibitors

by Poonam Kalhotra, Veera C.S.R. Chittepu, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velazquez
Published 2021-02-01

Phytochemicals in Garlic Extract Inhibit Therapeutic Enzyme DPP-4 and Induce Skeletal Muscle Cell Proliferation: A Possible Mechanism of Action to Benefit the Treatment of Diabetes...

by Poonam Kalhotra, Veera C.S.R. Chittepu, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velazquez
Published 2020-02-01

Discovery of Galangin as a Potential DPP-4 Inhibitor That Improves Insulin-Stimulated Skeletal Muscle Glucose Uptake: A Combinational Therapy for Diabetes

by Poonam Kalhotra, Veera C. S. R. Chittepu, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velázquez
Published 2019-03-01

Structure–Activity Relationship and Molecular Docking of Natural Product Library Reveal Chrysin as a Novel Dipeptidyl Peptidase-4 (DPP-4) Inhibitor: An Integrated In Silico and In...

by Poonam Kalhotra, Veera C. S. R. Chittepu, Guillermo Osorio-Revilla, Tzayhri Gallardo-Velázquez
Published 2018-06-01

Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study

by Veera C. S. R. Chittepu, Poonam Kalhotra, Tzayhri Osorio-Gallardo, Tzayhri Gallardo-Velázquez, Guillermo Osorio-Revilla
Published 2019-05-01

Designed Functional Dispersion for Insulin Protection from Pepsin Degradation and Skeletal Muscle Cell Proliferation: In Silico and In Vitro Study

by Veera C. S. R. Chittepu, Poonam Kalhotra, Tzayhri Gallardo-Velázquez, Raúl René Robles-de la Torre, Guillermo Osorio-Revilla
Published 2018-10-01

In Vitro Digestion of Microcapsule Carriers for Oral Delivery of Bioactive Compounds for Diabetes Treatment and Their Inhibitory Effect on the DPP-4 Enzyme

by Edwin García-Miguel, Veera C.S.R. Chittepu, Poonam Kalhotra, José Proal-Nájera, Guillermo Osorio-Revilla, Tzayhrí Gallardo-Velázquez
Published 2019-11-01

New Molecular Insights into the Inhibition of Dipeptidyl Peptidase-4 by Natural Cyclic Peptide Oxytocin

by Veera C. S. R. Chittepu, Poonam Kalhotra, Tzayhri Osorio-Gallardo, Cristian Jiménez-Martínez, Raúl René Robles-de la Torre, Tzayhri Gallardo-Velazquez, Guillermo Osorio-Revilla
Published 2019-10-01