Peripheral-Type Benzodiazepine Receptor Antagonist Is Effective in Relieving Neuropathic Pain in Mice

by Daisuke Kondo, Hironao Saegusa, Ritsuko Yabe, Ichiro Takasaki, Takashi Kurihara, Shuqin Zong, Tsutomu Tanabe
Published 2009-01-01

GPR40/FFAR1 deficient mice increase noradrenaline levels in the brain and exhibit abnormal behavior

by Fuka Aizawa, Takashi Nishinaka, Takuya Yamashita, Kazuo Nakamoto, Takashi Kurihara, Akira Hirasawa, Fumiyo Kasuya, Atsuro Miyata, Shogo Tokuyama
Published 2016-12-01

The novel small-molecule antagonist of PAC1 receptor attenuates formalin-induced inflammatory pain behaviors in mice

by Ichiro Takasaki, Koji Nakamura, Ayaka Shimodaira, Ai Watanabe, Huy Du Nguyen, Takuya Okada, Naoki Toyooka, Atsuro Miyata, Takashi Kurihara
Published 2019-02-01

Pituitary adenylate cyclase-activating polypeptide type 1 receptor signaling evokes long-lasting nociceptive behaviors through the activation of spinal astrocytes in mice

by Tetsuya Ohnou, Masafumi Yokai, Takashi Kurihara, Maiko Hasegawa-Moriyama, Takao Shimizu, Kazuhiko Inoue, Yuki Kambe, Yuichi Kanmura, Atsuro Miyata
Published 2016-04-01

Dysfunctional GPR40/FFAR1 signaling exacerbates pain behavior in mice.

by Kazuo Nakamoto, Fuka Aizawa, Kei Miyagi, Takuya Yamashita, Mitsumasa Mankura, Yutaka Koyama, Fumiyo Kasuya, Akira Hirasawa, Takashi Kurihara, Atsuro Miyata, Shogo Tokuyama
Published 2017-01-01

FFAR1/GPR40 Contributes to the Regulation of Striatal Monoamine Releases and Facilitation of Cocaine-Induced Locomotor Activity in Mice

by Yuko Sadamura, Yuko Sadamura, Shanta Thapa, Shanta Thapa, Ryota Mizunuma, Yuki Kambe, Akira Hirasawa, Kazuo Nakamoto, Shogo Tokuyama, Koji Yoshimoto, Kazunori Arita, Atsuro Miyata, Tatsuki Oyoshi, Takashi Kurihara
Published 2021-08-01