Inhibition of aberrant circulating Tfh cell proportions by corticosteroids in patients with systemic lupus erythematosus.

by Xuebing Feng, Dandan Wang, Jingjing Chen, Lin Lu, Bingzhu Hua, Xia Li, Betty P Tsao, Lingyun Sun
Published 2012-01-01

Transcription Factor SOX5 Promotes the Migration and Invasion of Fibroblast-Like Synoviocytes in Part by Regulating MMP-9 Expression in Collagen-Induced Arthritis

by Yumeng Shi, Qin Wu, Wenhua Xuan, Xiaoke Feng, Fang Wang, Betty P. Tsao, Miaojia Zhang, Wenfeng Tan
Published 2018-04-01

Reduced Let-7f in Bone Marrow-Derived Mesenchymal Stem Cells Triggers Treg/Th17 Imbalance in Patients With Systemic Lupus Erythematosus

by Linyu Geng, Linyu Geng, Xiaojun Tang, Shiying Wang, Yue Sun, Dandan Wang, Betty P. Tsao, Xuebing Feng, Lingyun Sun
Published 2020-02-01

ApoE−/−Fas−/− C57BL/6 mice: a novel murine model simultaneously exhibits lupus nephritis, atherosclerosis, and osteopenia

by Xuebing Feng, Hongyun Li, Alexis A. Rumbin, Xuping Wang, Antonio La Cava, Katherine Brechtelsbauer, Lawrence W. Castellani, Joseph L. Witztum, Aldons J. Lusis, Betty P. Tsao
Published 2007-04-01

A functional variant in microRNA-146a promoter modulates its expression and confers disease risk for systemic lupus erythematosus.

by Xiaobing Luo, Wanling Yang, Dong-Qing Ye, Huijuan Cui, Yan Zhang, Nattiya Hirankarn, Xiaoxia Qian, Yuanjia Tang, Yu Lung Lau, Niek de Vries, Paul Peter Tak, Betty P Tsao, Nan Shen
Published 2011-06-01

Genetic contributions to lupus nephritis in a multi-ethnic cohort of systemic lupus erythematous patients.

by Cristina M Lanata, Joanne Nititham, Kimberly E Taylor, Sharon A Chung, Dara G Torgerson, Michael F Seldin, Bernardo A Pons-Estel, Teresa Tusié-Luna, Betty P Tsao, Eric F Morand, Marta E Alarcón-Riquelme, Lindsey A Criswell
Published 2018-01-01

Rigorous Plasma Microbiome Analysis Method Enables Disease Association Discovery in Clinic

by Zhenwu Luo, Alexander V. Alekseyenko, Alexander V. Alekseyenko, Elizabeth Ogunrinde, Min Li, Quan-Zhen Li, Lei Huang, Betty P. Tsao, Diane L. Kamen, Jim C. Oates, Jim C. Oates, Zihai Li, Gary S. Gilkeson, Gary S. Gilkeson, Wei Jiang, Wei Jiang
Published 2021-01-01

Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes.

by Kimberly E Taylor, Sharon A Chung, Robert R Graham, Ward A Ortmann, Annette T Lee, Carl D Langefeld, Chaim O Jacob, M Ilyas Kamboh, Marta E Alarcón-Riquelme, Betty P Tsao, Kathy L Moser, Patrick M Gaffney, John B Harley, Michelle Petri, Susan Manzi, Peter K Gregersen, Timothy W Behrens, Lindsey A Criswell
Published 2011-02-01

Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production.

by Sharon A Chung, Kimberly E Taylor, Robert R Graham, Joanne Nititham, Annette T Lee, Ward A Ortmann, Chaim O Jacob, Marta E Alarcón-Riquelme, Betty P Tsao, John B Harley, Patrick M Gaffney, Kathy L Moser, SLEGEN, Michelle Petri, F Yesim Demirci, M Ilyas Kamboh, Susan Manzi, Peter K Gregersen, Carl D Langefeld, Timothy W Behrens, Lindsey A Criswell
Published 2011-03-01

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap.

by Paula S Ramos, Lindsey A Criswell, Kathy L Moser, Mary E Comeau, Adrienne H Williams, Nicholas M Pajewski, Sharon A Chung, Robert R Graham, Raphael Zidovetzki, Jennifer A Kelly, Kenneth M Kaufman, Chaim O Jacob, Timothy J Vyse, Betty P Tsao, Robert P Kimberly, Patrick M Gaffney, Marta E Alarcón-Riquelme, John B Harley, Carl D Langefeld, International Consortium on the Genetics of Systemic Erythematosus
Published 2011-12-01

Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus

by Prithvi Raj, Ran Song, Honglin Zhu, Linley Riediger, Dong-Jae Jun, Chaoying Liang, Carlos Arana, Bo Zhang, Yajing Gao, Benjamin E. Wakeland, Igor Dozmorov, Jinchun Zhou, Jennifer A. Kelly, Bernard R. Lauwerys, Joel M. Guthridge, Nancy J. Olsen, Swapan K. Nath, Chandrashekhar Pasare, Nicolai van Oers, Gary Gilkeson, Betty P. Tsao, Patrick M. Gaffney, Peter K. Gregersen, Judith A. James, Xiaoxia Zuo, David R. Karp, Quan-Zhen Li, Edward K. Wakeland
Published 2020-11-01

Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity

by Prithvi Raj, Ekta Rai, Ran Song, Shaheen Khan, Benjamin E Wakeland, Kasthuribai Viswanathan, Carlos Arana, Chaoying Liang, Bo Zhang, Igor Dozmorov, Ferdicia Carr-Johnson, Mitja Mitrovic, Graham B Wiley, Jennifer A Kelly, Bernard R Lauwerys, Nancy J Olsen, Chris Cotsapas, Christine K Garcia, Carol A Wise, John B Harley, Swapan K Nath, Judith A James, Chaim O Jacob, Betty P Tsao, Chandrashekhar Pasare, David R Karp, Quan Zhen Li, Patrick M Gaffney, Edward K Wakeland
Published 2016-02-01

Amino acid signatures of HLA Class-I and II molecules are strongly associated with SLE susceptibility and autoantibody production in Eastern Asians.

by Julio E Molineros, Loren L Looger, Kwangwoo Kim, Yukinori Okada, Chikashi Terao, Celi Sun, Xu-Jie Zhou, Prithvi Raj, Yuta Kochi, Akari Suzuki, Shuji Akizuki, Shuichiro Nakabo, So-Young Bang, Hye-Soon Lee, Young Mo Kang, Chang-Hee Suh, Won Tae Chung, Yong-Beom Park, Jung-Yoon Choe, Seung-Cheol Shim, Shin-Seok Lee, Xiaoxia Zuo, Kazuhiko Yamamoto, Quan-Zhen Li, Nan Shen, Lauren L Porter, John B Harley, Kek Heng Chua, Hong Zhang, Edward K Wakeland, Betty P Tsao, Sang-Cheol Bae, Swapan K Nath
Published 2019-04-01

Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.

by Julio E Molineros, Amit K Maiti, Celi Sun, Loren L Looger, Shizhong Han, Xana Kim-Howard, Stuart Glenn, Adam Adler, Jennifer A Kelly, Timothy B Niewold, Gary S Gilkeson, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Michelle Petri, Rosalind Ramsey-Goldman, John D Reveille, Luis M Vilá, Barry I Freedman, Betty P Tsao, Lindsey A Criswell, Chaim O Jacob, Jason H Moore, Timothy J Vyse, Carl L Langefeld, Joel M Guthridge, Patrick M Gaffney, Kathy L Moser, R Hal Scofield, Marta E Alarcón-Riquelme, BIOLUPUS Network, Scott M Williams, Joan T Merrill, Judith A James, Kenneth M Kaufman, Robert P Kimberly, John B Harley, Swapan K Nath
Published 2013-01-01

Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.

by Harinder Manku, Carl D Langefeld, Sandra G Guerra, Talat H Malik, Marta Alarcon-Riquelme, Juan-Manuel Anaya, Sang-Cheol Bae, Susan A Boackle, Elizabeth E Brown, Lindsey A Criswell, Barry I Freedman, Patrick M Gaffney, Peter A Gregersen, Joel M Guthridge, Sang-Hoon Han, John B Harley, Chaim O Jacob, Judith A James, Diane L Kamen, Kenneth M Kaufman, Jennifer A Kelly, Javier Martin, Joan T Merrill, Kathy L Moser, Timothy B Niewold, So-Yeon Park, Bernardo A Pons-Estel, Amr H Sawalha, R Hal Scofield, Nan Shen, Anne M Stevens, Celi Sun, Gary S Gilkeson, Jeff C Edberg, Robert P Kimberly, Swapan K Nath, Betty P Tsao, Tim J Vyse
Published 2013-01-01

MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.

by Yun Deng, Jian Zhao, Daisuke Sakurai, Kenneth M Kaufman, Jeffrey C Edberg, Robert P Kimberly, Diane L Kamen, Gary S Gilkeson, Chaim O Jacob, R Hal Scofield, Carl D Langefeld, Jennifer A Kelly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Timothy J Vyse, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Peter K Gregersen, Juan-Manuel Anaya, Timothy B Niewold, Joan T Merrill, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Rita M Cantor, Weiling Chen, Jeniffer M Grossman, Bevra H Hahn, John B Harley, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Elizabeth E Brown, Betty P Tsao
Published 2013-01-01

PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.

by Bahram Namjou, Xana Kim-Howard, Celi Sun, Adam Adler, Sharon A Chung, Kenneth M Kaufman, Jennifer A Kelly, Stuart B Glenn, Joel M Guthridge, Robert H Scofield, Robert P Kimberly, Elizabeth E Brown, Graciela S Alarcón, Jeffrey C Edberg, Jae-Hoon Kim, Jiyoung Choi, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Susan A Boackle, Barry I Freedman, Betty P Tsao, Carl D Langefeld, Timothy J Vyse, Chaim O Jacob, Bernardo Pons-Estel, Argentine Collaborative Group, Timothy B Niewold, Kathy L Moser Sivils, Joan T Merrill, Juan-Manuel Anaya, Gary S Gilkeson, Patrick M Gaffney, Sang-Cheol Bae, Marta E Alarcón-Riquelme, BIOLUPUS and GENLES Networks, John B Harley, Lindsey A Criswell, Judith A James, Swapan K Nath
Published 2013-01-01

Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.

by Daisuke Sakurai, Jian Zhao, Yun Deng, Jennifer A Kelly, Elizabeth E Brown, John B Harley, Sang-Cheol Bae, Marta E Alarcόn-Riquelme, BIOLUPUS and GENLES networks, Jeffrey C Edberg, Robert P Kimberly, Rosalind Ramsey-Goldman, Michelle A Petri, John D Reveille, Luis M Vilá, Graciela S Alarcón, Kenneth M Kaufman, Timothy J Vyse, Chaim O Jacob, Patrick M Gaffney, Kathy Moser Sivils, Judith A James, Diane L Kamen, Gary S Gilkeson, Timothy B Niewold, Joan T Merrill, R Hal Scofield, Lindsey A Criswell, Anne M Stevens, Susan A Boackle, Jae-Hoon Kim, Jiyoung Choi, Bernardo A Pons-Estel, Argentine Collaborative Group, Barry I Freedman, Juan-Manuel Anaya, Javier Martin, C Yung Yu, Deh-Ming Chang, Yeong Wook Song, Carl D Langefeld, Weiling Chen, Jennifer M Grossman, Rita M Cantor, Bevra H Hahn, Betty P Tsao
Published 2013-01-01

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.

by Jian Zhao, Hui Wu, Melanie Khosravi, Huijuan Cui, Xiaoxia Qian, Jennifer A Kelly, Kenneth M Kaufman, Carl D Langefeld, Adrienne H Williams, Mary E Comeau, Julie T Ziegler, Miranda C Marion, Adam Adler, Stuart B Glenn, Marta E Alarcón-Riquelme, BIOLUPUS Network, GENLES Network, Bernardo A Pons-Estel, John B Harley, Sang-Cheol Bae, So-Young Bang, Soo-Kyung Cho, Chaim O Jacob, Timothy J Vyse, Timothy B Niewold, Patrick M Gaffney, Kathy L Moser, Robert P Kimberly, Jeffrey C Edberg, Elizabeth E Brown, Graciela S Alarcon, Michelle A Petri, Rosalind Ramsey-Goldman, Luis M Vilá, John D Reveille, Judith A James, Gary S Gilkeson, Diane L Kamen, Barry I Freedman, Juan-Manuel Anaya, Joan T Merrill, Lindsey A Criswell, R Hal Scofield, Anne M Stevens, Joel M Guthridge, Deh-Ming Chang, Yeong Wook Song, Ji Ah Park, Eun Young Lee, Susan A Boackle, Jennifer M Grossman, Bevra H Hahn, Timothy H J Goodship, Rita M Cantor, Chack-Yung Yu, Nan Shen, Betty P Tsao
Published 2011-05-01

Lupus risk variants in the PXK locus alter B-cell receptor internalization

by Samuel E. Vaughn, Samuel E. Vaughn, Corinne eFoley, Corinne eFoley, Xiaoming eLu, Zubin Hasmukh Patel, Zubin Hasmukh Patel, Erin E. Zoller, Albert F. Magnusen, Adrienne H. Williams, Julie T. Ziegler, Mary E. Comeau, Miranda C. Marion, Stuart B. Glenn, Adam eAdler, Nan eShen, Nan eShen, Swapan eNath, Anne M Stevens, Anne M Stevens, Barry I. Freedman, Betty P. Tsao, Chaim O. Jacob, Diane L Kamen, Elizabeth E Brown, Elizabeth E Brown, Gary S. Gilkeson, Graciela S. Alarcón, John D. Reveille, Juan-Manuel eAnaya, Judith A. James, Judith A. James, Kathy L. Moser, Lindsey A. Criswell, Luis M. Vilá, Marta E. Alarcon-Riquelme, Marta E. Alarcon-Riquelme, Michelle ePetri, R. Hal Scofield, R. Hal Scofield, R. Hal Scofield, Robert P. Kimberly, Rosalind eRamsey-Goldman, Young eBinjoo, Jeongim eChoi, Sang-Cheol eBae, Susan A. Boackle, Timothy J. Vyse, Joel M. Guthridge, Bahram eNamjou, Patrick M. Gaffney, Carl D. Langefeld, Kenneth M. Kaufman, Kenneth M. Kaufman, Jennifer A Kelly, Isaac TW Harley, John Barker Harley, John Barker Harley, Leah Claire Kottyan, Leah Claire Kottyan
Published 2015-01-01