Inhibition of histone deacetylases 1 and 6 enhances cytarabine-induced apoptosis in pediatric acute myeloid leukemia cells.

by Xuelian Xu, Chengzhi Xie, Holly Edwards, Hui Zhou, Steven A Buck, Yubin Ge
Published 2011-01-01

Overexpression of GATA1 confers resistance to chemotherapy in acute megakaryocytic Leukemia.

by John Timothy Caldwell, Holly Edwards, Alan A Dombkowski, Steven A Buck, Larry H Matherly, Yubin Ge, Jeffrey W Taub
Published 2013-01-01

Panobinostat synergistically enhances the cytotoxic effects of cisplatin, doxorubicin or etoposide on high-risk neuroblastoma cells.

by Guan Wang, Holly Edwards, J Timothy Caldwell, Steven A Buck, William Y Qing, Jeffrey W Taub, Yubin Ge, Zhihong Wang
Published 2013-01-01

Panobinostat enhances cytarabine and daunorubicin sensitivities in AML cells through suppressing the expression of BRCA1, CHK1, and Rad51.

by Chengzhi Xie, Christina Drenberg, Holly Edwards, J Timothy Caldwell, Wei Chen, Hiroto Inaba, Xuelian Xu, Steven A Buck, Jeffrey W Taub, Sharyn D Baker, Yubin Ge
Published 2013-01-01

A unique role of GATA1s in Down syndrome acute megakaryocytic leukemia biology and therapy.

by Ana C Xavier, Holly Edwards, Alan A Dombkowski, Tugce B Balci, Jason N Berman, Graham Dellaire, Chengzhi Xie, Steven A Buck, Larry H Matherly, Yubin Ge, Jeffrey W Taub
Published 2011-01-01