Ric-8A, a G protein chaperone with nucleotide exchange activity induces long-range secondary structure changes in Gα

by Ravi Kant, Baisen Zeng, Celestine J Thomas, Brian Bothner, Stephen R Sprang
Published 2016-12-01

Crystal structure of the major quadruplex formed in the promoter region of the human c-MYC oncogene.

by Sascha Stump, Tung-Chung Mou, Stephen R Sprang, Nicholas R Natale, Howard D Beall
Published 2018-01-01

The structure of the cysteine-rich region from human histone-lysine N-methyltransferase EHMT2 (G9a)

by Keshia M. Kerchner, Tung-Chung Mou, Yizhi Sun, Domniţa-Valeria Rusnac, Stephen R. Sprang, Klára Briknarová
Published 2021-01-01

Biochemical reconstitution of hemorrhagic-fever arenavirus envelope glycoprotein-mediated membrane fusion.

by Celestine J Thomas, Sundaresh Shankar, Hedi E Casquilho-Gray, Joanne York, Stephen R Sprang, Jack H Nunberg
Published 2012-01-01

The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1.

by Celestine J Thomas, Klára Briknarová, Jonathan K Hilmer, Navid Movahed, Brian Bothner, John P Sumida, Gregory G Tall, Stephen R Sprang
Published 2011-01-01

Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

by Levi J. McClelland, Kaiming Zhang, Tung-Chung Mou, Jake Johnston, Cindee Yates-Hansen, Shanshan Li, Celestine J. Thomas, Tzanko I. Doukov, Sarah Triest, Alexandre Wohlkonig, Gregory G. Tall, Jan Steyaert, Wah Chiu, Stephen R. Sprang
Published 2020-02-01