Discovery and characterization of a novel cyclic peptide that effectively inhibits ephrin binding to the EphA4 receptor and displays anti-angiogenesis activity.

by Xiaofeng Han, Yan Xu, Yilei Yang, Jingle Xi, Wang Tian, Srinivas Duggineni, Ziwei Huang, Jing An
Published 2013-01-01

PEGylation potentiates the effectiveness of an antagonistic peptide that targets the EphB4 receptor with nanomolar affinity.

by Roberta Noberini, Sayantan Mitra, Ombretta Salvucci, Fatima Valencia, Srinivas Duggineni, Natalie Prigozhina, Ke Wei, Giovanna Tosato, Ziwei Huang, Elena B Pasquale
Published 2011-01-01