The Combination of MK-2206 and WZB117 Exerts a Synergistic Cytotoxic Effect Against Breast Cancer Cells

by Yu-Liang Li, Hao-Cheng Weng, Jui-Ling Hsu, Shu-Wha Lin, Jih-Hwa Guh, Lih-Ching Hsu
Published 2019-11-01

Lack of Thromboxane Synthase Prevents Hypertension and Fetal Growth Restriction after High Salt Treatment during Pregnancy.

by Chen-Hsueh Pai, Ching-Tzu Yen, Chie-Pein Chen, I-Shing Yu, Shu-Wha Lin, Shu-Rung Lin
Published 2016-01-01

Hepatocyte-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Produce Functional Coagulation Factor IX in a Hemophilia B Mouse Model

by Yao-Ming Wu, Yu-Jen Huang, Poda Chen, Yu-Chen Hsu, Shu-Wha Lin, Hong-Shiee Lai, Hsuan-Shu Lee
Published 2016-07-01

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells.

by Chun-Yu Chen, I-Shing Yu, Chen-Hsueh Pai, Chien-Yu Lin, Shu-Rung Lin, You-Tzung Chen, Shu-Wha Lin
Published 2019-01-01

Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice.

by Chun-Kai Chang, Xiu-Ru Lin, Yen-Lin Lin, Woei-Horng Fang, Shu-Wha Lin, Sui-Yuan Chang, Jau-Tsuen Kao
Published 2018-01-01

Acquired FXIII inhibitor: Patient characteristics and treatment outcome, a case series in Taiwan

by Sheng-Chieh Chou, Ching-Yeh Lin, Ching-Tzu Yen, Han-Ni Hsieh, Ying-Chih Huang, Ko-Jen Li, Shu-Wha Lin, Ming-Ching Shen
Published 2021-01-01

Sun1 deficiency leads to cerebellar ataxia in mice

by Jing-Ya Wang, I.-Shing Yu, Chien-Chi Huang, Chia-Yen Chen, Wan-Ping Wang, Shu-Wha Lin, Kuan-Teh Jeang, Ya-Hui Chi
Published 2015-08-01

Genetic Modification of Donor Hepatocytes Improves Therapeutic Efficacy for Hemophilia B in Mice

by Yao-Ming Wu, Chung-Yang Kao, Yu-Jen Huang, I-Shing Yu, Hsuan-Shu Lee, Hong-Shiee Lai, Po-Huang Lee, Chia-Ni Lin, Shu-Wha Lin
Published 2010-09-01

SEPT12-Microtubule Complexes Are Required for Sperm Head and Tail Formation

by Yen-Ni Teng, Ying-Hung Lin, Shu-Wha Lin, I-Shing Yu, Mei-Feng Chen, Pao-Lin Kuo, Yung-Che Kuo, Ya-Yun Wang, Han-Sun Chiang
Published 2013-11-01

Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis

by Brian D. Adair, José L. Alonso, Johannes van Agthoven, Vincent Hayes, Hyun Sook Ahn, I-Shing Yu, Shu-Wha Lin, Jian-Ping Xiong, Mortimer Poncz, M. Amin Arnaout
Published 2020-01-01

Differences in the pathogenicity of the p.H723R mutation of the common deafness-associated SLC26A4 gene in humans and mice.

by Ying-Chang Lu, Chen-Chi Wu, Ting-Hua Yang, Yin-Hung Lin, I-Shing Yu, Shu-Wha Lin, Qing Chang, Xi Lin, Jau-Min Wong, Chuan-Jen Hsu
Published 2014-01-01

Targeting fibroblast CD248 attenuates CCL17-expressing macrophages and tissue fibrosis

by Chen-Hsueh Pai, Shu-Rung Lin, Chia-Hao Liu, Szu-Yu Pan, Hao Hsu, Yi-Ting Chen, Ching-Tzu Yen, I-Shing Yu, Hua-Lin Wu, Shuei-Liong Lin, Shu-Wha Lin
Published 2020-10-01

A Double Negative Loop Comprising ETV6/RUNX1 and MIR181A1 Contributes to Differentiation Block in t(12;21)-Positive Acute Lymphoblastic Leukemia.

by Yung-Li Yang, Ching-Tzu Yen, Chen-Hsueh Pai, Hsuan-Yu Chen, Sung-Liang Yu, Chien-Yu Lin, Chung-Yi Hu, Shiann-Tarng Jou, Dong-Tsamn Lin, Shu-Rung Lin, Shu-Wha Lin
Published 2015-01-01

Toward the Pathogenicity of the<i> SLC26A4 </i>p.C565Y Variant Using a Genetically Driven Mouse Model

by Chin-Ju Hu, Ying-Chang Lu, Ting-Hua Yang, Yen-Hui Chan, Cheng-Yu Tsai, I-Shing Yu, Shu-Wha Lin, Tien-Chen Liu, Yen-Fu Cheng, Chen-Chi Wu, Chuan-Jen Hsu
Published 2021-03-01

Establishment of a knock-in mouse model with the SLC26A4 c.919-2A>G mutation and characterization of its pathology.

by Ying-Chang Lu, Chen-Chi Wu, Wen-Sheng Shen, Ting-Hua Yang, Te-Huei Yeh, Pei-Jer Chen, I-Shing Yu, Shu-Wha Lin, Jau-Min Wong, Qing Chang, Xi Lin, Chuan-Jen Hsu
Published 2011-01-01

Cardiac-specific microRNA-125b deficiency induces perinatal death and cardiac hypertrophy

by Chen-Yun Chen, Desy S. Lee, Oi Kuan Choong, Sheng-Kai Chang, Tien Hsu, Martin W. Nicholson, Li-Wei Liu, Po-Ju Lin, Shu-Chian Ruan, Shu-Wha Lin, Chung-Yi Hu, Patrick C. H. Hsieh
Published 2021-01-01

Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia

by Ya-Hsuan Chang, Chih-Hsiang Yu, Shiann-Tarng Jou, Chien-Yu Lin, Kai-Hsin Lin, Meng-Yao Lu, Kang-Hsi Wu, Hsiu-Hao Chang, Dong-Tsamn Lin, Shu-Wha Lin, Hsuan-Yu Chen, Yung-Li Yang
Published 2021-01-01

MicroRNA-221/222 Mediates ADSC-Exosome-Induced Cardioprotection Against Ischemia/Reperfusion by Targeting PUMA and ETS-1

by Tsai-Chun Lai, Tzu-Lin Lee, Yu-Chun Chang, Yu-Chen Chen, Shu-Rung Lin, Shu-Rung Lin, Shu-Wha Lin, Chi-Ming Pu, Chi-Ming Pu, Jaw-Shiun Tsai, Jaw-Shiun Tsai, Yuh-Lien Chen
Published 2020-12-01

A nucleolus-predominant piggyBac transposase, NP-mPB, mediates elevated transposition efficiency in mammalian cells.

by Jin-Bon Hong, Fu-Ju Chou, Amy T Ku, Hsiang-Hsuan Fan, Tung-Lung Lee, Yung-Hsin Huang, Tsung-Lin Yang, I-Chang Su, I-Shing Yu, Shu-Wha Lin, Chung-Liang Chien, Hong-Nerng Ho, You-Tzung Chen
Published 2014-01-01

Differential cell-intrinsic regulations of germinal center B and T cells by miR-146a and miR-146b

by Sunglim Cho, Hyang-Mi Lee, I-Shing Yu, Youn Soo Choi, Hsi-Yuan Huang, Somaye Sadat Hashemifar, Ling-Li Lin, Mei-Chi Chen, Nikita D. Afanasiev, Aly Azeem Khan, Shu-Wha Lin, Alexander Y. Rudensky, Shane Crotty, Li-Fan Lu
Published 2018-07-01