NK-4 exerts selective regulatory effects on the activation and function of allergy-related Th2 cells.

by Keizo Kohno, Satomi Koya-Miyata, Akira Harashima, Toshio Ariyasu, Shimpei Ushio
Published 2018-01-01

Effects of a non-cyclodextrin cyclic carbohydrate on mouse melanoma cells: Characterization of a new type of hypopigmenting sugar.

by Shuji Nakamura, Toshio Kunikata, Yohsuke Matsumoto, Toshiharu Hanaya, Akira Harashima, Tomoyuki Nishimoto, Shimpei Ushio
Published 2017-01-01

Daily consumption of one teaspoon of trehalose can help maintain glucose homeostasis: a double-blind, randomized controlled trial conducted in healthy volunteers

by Chiyo Yoshizane, Akiko Mizote, Chikako Arai, Norie Arai, Rieko Ogawa, Shin Endo, Hitoshi Mitsuzumi, Shimpei Ushio
Published 2020-07-01

Response to: can one teaspoon of trehalose a day mitigate metabolic syndrome and diabetes risks?

by Chiyo Yoshizane, Akiko Mizote, Chikako Arai, Norie Arai, Rieko Ogawa, Shin Endo, Hitoshi Mitsuzumi, Shimpei Ushio
Published 2021-03-01

Inflammatory M1-like macrophages polarized by NK-4 undergo enhanced phenotypic switching to an anti-inflammatory M2-like phenotype upon co-culture with apoptotic cells

by Keizo Kohno, Satomi Koya-Miyata, Akira Harashima, Takahiko Tsukuda, Masataka Katakami, Toshio Ariyasu, Shimpei Ushio, Kanso Iwaki
Published 2021-01-01

Effects of isomaltodextrin in postprandial lipid kinetics: Rat study and human randomized crossover study.

by Ryodai Takagaki, Yuki Ishida, Tsuyoshi Sadakiyo, Yoshifumi Taniguchi, Takeo Sakurai, Hitoshi Mitsuzumi, Hikaru Watanabe, Shigeharu Fukuda, Shimpei Ushio
Published 2018-01-01

Continuous intake of Trehalose induces white adipose tissue Browning and Enhances energy metabolism

by Chikako Arai, Norie Arai, Shigeyuki Arai, Chiyo Yoshizane, Satomi Miyata, Akiko Mizote, Aki Suyama, Shin Endo, Toshio Ariyasu, Hitoshi Mitsuzumi, Shimpei Ushio
Published 2019-07-01

Trehalose itself plays a critical role on lipid metabolism: Trehalose increases jejunum cytoplasmic lipid droplets which negatively correlated with mesenteric adipocyte size in bot...

by Chikako Arai, Aki Suyama, Shigeyuki Arai, Norie Arai, Chiyo Yoshizane, Satomi Koya-Miyata, Akiko Mizote, Shin Endo, Toshio Ariyasu, Hitoshi Mitsuzumi, Shimpei Ushio
Published 2020-03-01