A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

by Schmidt, Florian I., Lu, Alvin, Chen, Jeff W., Ruan, Jianbin, Tang, Catherine, Wu, Hao, Ploegh, Hidde
Published 2017

Phenotypic lentivirus screens to identify functional single domain antibodies

by Schmidt, Florian I., Hanke, Leo, Morin, Benjamin, Brewer, Rebeccah, Brusic, Vesna, Whelan, Sean P.J, Ploegh, Hidde
Published 2017

The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment

by Hanke, Leo, Brewer, R. Camille, van Diest, Eline, Schmidt, Florian I., Schwartz, Thomas, Knockenhauer, Kevin Edward, Ploegh, Hidde
Published 2017

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

by Tafesse, Fikadu G., Rashidfarrokhi, Ali, Freinkman, Elizaveta, Dougan, Stephanie, Dougan, Michael, Esteban, Alexandre, Maruyama, Takeshi, Strijbis, Karin, Schmidt, Florian Ingo, Ploegh, Hidde
Published 2017

The E2 Ubiquitin-conjugating Enzyme UBE2J1 Is Required for Spermiogenesis in Mice

by Koenig, Paul-Albert, Hagiwara, Masatoshi, Maruyama, Takeshi, Watson, Nicki, Page, David C, Nicholls, Peter, Schmidt, Florian Ingo, Ploegh, Hidde, Frydman, Galit H.
Published 2017

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism

by Lu, Alvin, Li, Yang, Schmidt, Florian I, Yin, Qian, Chen, Shuobing, Fu, Tian-Min, Tong, Alexander B, Mao, Youdong, Wu, Hao, Ploegh, Hidde
Published 2017

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

by Chow, Ryan D, Guzman, Christopher D, Wang, Guangchuan, Schmidt, Florian, Youngblood, Mark W, Ye, Lupeng, Errami, Youssef, Dong, Matthew B, Martinez, Michael A, Zhang, Sensen, Renauer, Paul, Bilguvar, Kaya, Gunel, Murat, Zhang, Feng, Platt, Randall J, Chen, Sidi, Sharp, Phillip A.
Published 2018