Planarians SET New Paths for Innate Immune Memory

by Samuel T. Keating, Niels P. Riksen, Mihai G. Netea
Published 2017-06-01

Cytokines and microbicidal molecules regulated by IL-32 in THP-1-derived human macrophages infected with New World Leishmania species.

by Jéssica Cristina Dos Santos, Bas Heinhuis, Rodrigo Saar Gomes, Michelle S M A Damen, Fernando Real, Renato A Mortara, Samuel T Keating, Charles A Dinarello, Leo A B Joosten, Fátima Ribeiro-Dias
Published 2017-02-01

Genetic variation in Interleukin-32 influence the immune response against New World Leishmania species and susceptibility to American Tegumentary Leishmaniasis.

by Jéssica Cristina Dos Santos, Valéria Bernadete Leite Quixabeira, Muriel Vilela Teodoro Silva, Michelle S M A Damen, Kiki Schraa, Martin Jaeger, Marije Oosting, Samuel T Keating, Miriam Leandro Dorta, Sebastião Alves Pinto, Fernanda Bugalho Duarte, Ledice Inácia de Araújo Pereira, Mihai G Netea, Fátima Ribeiro-Dias, Leo A B Joosten
Published 2020-02-01

β-Glucan-Induced Trained Immunity Protects against Leishmania braziliensis Infection: a Crucial Role for IL-32

by Jéssica Cristina dos Santos, Ana Marina Barroso de Figueiredo, Muriel Vilela Teodoro Silva, Branko Cirovic, L. Charlotte J. de Bree, Michelle S.M.A. Damen, Simone J.C.F.M. Moorlag, Rodrigo S. Gomes, Monique M. Helsen, Marije Oosting, Samuel T. Keating, A. Schlitzer, Mihai G. Netea, Fátima Ribeiro-Dias, Leo A.B. Joosten
Published 2019-09-01

The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan

by Samuel T. Keating, Laszlo Groh, Charlotte D.C.C. van der Heijden, Hanah Rodriguez, Jéssica C. dos Santos, Stephanie Fanucchi, Jun Okabe, Harikrishnan Kaipananickal, Jelmer H. van Puffelen, Leonie Helder, Marlies P. Noz, Vasiliki Matzaraki, Yang Li, L. Charlotte J. de Bree, Valerie A.C.M. Koeken, Simone J.C.F.M. Moorlag, Vera P. Mourits, Jorge Domínguez-Andrés, Marije Oosting, Elianne P. Bulthuis, Werner J.H. Koopman, Musa Mhlanga, Assam El-Osta, Leo A.B. Joosten, Mihai G. Netea, Niels P. Riksen
Published 2020-04-01