842 A novel agonistic anti-CD40 targeting strategy with an affinity peptide binding feature for antigen cargo functionality: improving peptide stability and T cell proliferation

by Ida Olsson, Mohamed Eltahir, Sara Mangsbo
Published 2020-11-01

Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential

by Espen Basmo Ellingsen, Espen Basmo Ellingsen, Espen Basmo Ellingsen, Sara M. Mangsbo, Sara M. Mangsbo, Eivind Hovig, Eivind Hovig, Gustav Gaudernack
Published 2021-07-01

Cancer Vaccines: Adjuvant Potency, Importance of Age, Lifestyle, and Treatments

by Stefania Cuzzubbo, Stefania Cuzzubbo, Sara Mangsbo, Sara Mangsbo, Divya Nagarajan, Kinana Habra, Kinana Habra, Alan Graham Pockley, Alan Graham Pockley, Stephanie E. B. McArdle, Stephanie E. B. McArdle
Published 2021-02-01

Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients

by A. Schiza, J. Wenthe, S. Mangsbo, E. Eriksson, Anders Nilsson, T. H. Tötterman, A. Loskog, G. Ullenhag
Published 2017-04-01

The use of multiplex platforms for absolute and relative protein quantification of clinical material

by Lisa Christiansson, Satu Mustjoki, Bengt Simonsson, Ulla Olsson-Strömberg, Angelica S.I. Loskog, Sara M. Mangsbo
Published 2014-06-01

Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade

by Mohamed Eltahir, Johan Isaksson, Johanna Sofia Margareta Mattsson, Klas Kärre, Johan Botling, Martin Lord, Sara M. Mangsbo, Patrick Micke
Published 2021-06-01

Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic interventio...

by Aikaterini Nasi, Stephanie McArdle, Gustav Gaudernack, Gabriel Westman, Cornelis Melief, Johan Rockberg, Ramon Arens, Demetrios Kouretas, Jan Sjölin, Sara Mangsbo
Published 2020-01-01

Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations...

by Iliana K Kerzeli, Martin Lord, Milena Doroszko, Ramy Elgendy, Aikaterini Chourlia, Ivan Stepanek, Elinor Larsson, Luuk van Hooren, Sven Nelander, Per-Uno Malmstrom, Anca Dragomir, Ulrika Segersten, Sara M Mangsbo
Published 2021-01-01

Antibody responses after a single dose of ChAdOx1 nCoV-19 vaccine in healthcare workers previously infected with SARS-CoV-2

by Sebastian Havervall, Ulrika Marking, Nina Greilert-Norin, Henry Ng, Max Gordon, Ann-Christin Salomonsson, Cecilia Hellström, Elisa Pin, Kim Blom, Sara Mangsbo, Mia Phillipson, Jonas Klingström, Sophia Hober, Peter Nilsson, Mikael Åberg, Charlotte Thålin
Published 2021-08-01

BCG‐induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

by Cristián Ibarra, Marie Karlsson, Simone Codeluppi, Manuel Varas‐Godoy, Songbai Zhang, Lauri Louhivuori, Sara Mangsbo, Arad Hosseini, Navid Soltani, Rahim Kaba, T. Kalle Lundgren, Abolfazl Hosseini, Nobuyuki Tanaka, Mototsugu Oya, Peter Wiklund, Ayako Miyakawa, Per Uhlén
Published 2019-02-01

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

by Maria Georganaki, Mohanraj Ramachandran, Sander Tuit, Nicolás Gonzalo Núñez, Alexandros Karampatzakis, Grammatiki Fotaki, Luuk van Hooren, Hua Huang, Roberta Lugano, Thomas Ulas, Aura Kaunisto, Eric C Holland, Peter Ellmark, Sara M Mangsbo, Joachim Schultze, Magnus Essand, Sonia Tugues, Anna Dimberg
Published 2020-01-01

Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma

by Luuk van Hooren, Alessandra Vaccaro, Mohanraj Ramachandran, Konstantinos Vazaios, Sylwia Libard, Tiarne van de Walle, Maria Georganaki, Hua Huang, Ilkka Pietilä, Joey Lau, Maria H. Ulvmar, Mikael C. I. Karlsson, Maria Zetterling, Sara M. Mangsbo, Asgeir S. Jakola, Thomas Olsson Bontell, Anja Smits, Magnus Essand, Anna Dimberg
Published 2021-07-01