Altered gene expression in blood and sputum in COPD frequent exacerbators in the ECLIPSE cohort.

by Dave Singh, Steven M Fox, Ruth Tal-Singer, Stewart Bates, John H Riley, Bartolome Celli
Published 2014-01-01

Multiple biomarkers predict disease severity, progression and mortality in COPD

by Rachel L. Zemans, Sean Jacobson, Jason Keene, Katerina Kechris, Bruce E. Miller, Ruth Tal-Singer, Russell P. Bowler
Published 2017-06-01

CXCR2 antagonist for patients with chronic obstructive pulmonary disease with chronic mucus hypersecretion: a phase 2b trial

by Aili L. Lazaar, Bruce E. Miller, Alison C. Donald, Thomas Keeley, Claire Ambery, John Russell, Henrik Watz, Ruth Tal-Singer, for 205724 Investigators
Published 2020-06-01

DSP variants may be associated with longitudinal change in quantitative emphysema

by Woori Kim, Michael H. Cho, Phuwanat Sakornsakolpat, David A. Lynch, Harvey O. Coxson, Ruth Tal-Singer, Edwin K. Silverman, Terri H. Beaty
Published 2019-07-01

CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin

by Holly R. Keir, Hollian Richardson, Christina Fillmore, Amelia Shoemark, Aili L. Lazaar, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers, Divya Mohan
Published 2020-11-01

Plasma microfibrillar-associated protein 4 is not prognostic of emphysema progression but is associated with cardiovascular disease history and mortality in COPD patients

by Sofie Lock Johansson, Helle Wulf-Johansson, Anders Schlosser, Ingrid L. Titlestad, Bruce Miller, Ruth Tal-Singer, Uffe Holmskov, Jørgen Vestbo, Grith Lykke Sørensen
Published 2019-04-01

P7.14 SERUM INFLAMMATORY MARKERS ARE POOR PREDICTORS OF VASCULAR INFLAMMATION AND VASCULAR INFLAMMATION DOES NOT DETERMINE AORTIC STIFFNESS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE...

by Marie Fisk*, Divya Mohan, Joseph Cheriyan, Julia Forman, Carmel M. McEniery, John R. Cockcroft, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson
Published 2015-11-01

Blood neutrophil counts are associated with exacerbation frequency and mortality in COPD

by Mike Lonergan, Alison J. Dicker, Megan L. Crichton, Holly R. Keir, Melissa K. Van Dyke, Hana Mullerova, Bruce E. Miller, Ruth Tal-Singer, James D. Chalmers
Published 2020-07-01

Endotrophin, an extracellular hormone, in combination with neoepitope markers of von Willebrand factor improves prediction of mortality in the ECLIPSE COPD cohort

by Sarah R. Rønnow, Lasse L. Langholm, Morten A. Karsdal, Tina Manon-Jensen, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana J. Leeming, Jannie M. B. Sand
Published 2020-07-01

Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort

by Sarah Rank Rønnow, Jannie Marie Bülow Sand, Lasse Løcke Langholm, Tina Manon-Jensen, Morten Asser Karsdal, Ruth Tal-Singer, Bruce E. Miller, Jørgen Vestbo, Diana Julie Leeming
Published 2019-04-01

Quantitative analysis of dynamic 18F-FDG PET/CT for measurement of lung inflammation

by Christopher Coello, Marie Fisk, Divya Mohan, Frederick J. Wilson, Andrew P. Brown, Michael I. Polkey, Ian Wilkinson, Ruth Tal-Singer, Philip S. Murphy, Joseph Cheriyan, Roger N. Gunn
Published 2017-05-01

Vascular inflammation and aortic stiffness: potential mechanisms of increased vascular risk in chronic obstructive pulmonary disease

by Marie Fisk, Joseph Cheriyan, Divya Mohan, Carmel M. McEniery, Julia Forman, John R. Cockcroft, James H. F. Rudd, Ruth Tal-Singer, Nicholas S. Hopkinson, Michael I. Polkey, Ian B. Wilkinson
Published 2018-05-01

Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis

by Rosa Faner, Jarrett D. Morrow, Sandra Casas-Recasens, Suzanne M. Cloonan, Guillaume Noell, Alejandra López-Giraldo, Ruth Tal-Singer, Bruce E. Miller, Edwin K. Silverman, Alvar Agustí, Craig P. Hersh
Published 2019-01-01

1.6 THE BODE INDEX PROGNOSTIC SCORE IS AN INDEPENDENT DETERMINANT OF ARTERIAL STIFFNESS IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)

by Marie Fisk*, Nichola Gale, Divya Mohan, Carmel M. McEniery, Julia Forman, Charlotte E. Bolton, William MacNee, John R. Cockcroft, Joseph Cheriyan, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson
Published 2015-11-01

Investigation of the Clinical, Radiological and Biological Factors Associated with Disease Progression, Phenotypes and Endotypes of COPD in China (COMPASS): study design, protocol...

by Zhenyu Liang, Nanshan Zhong, Rongchang Chen, Qianli Ma, Yongchang Sun, Fuqiang Wen, Ruth Tal-Singer, Bruce E. Miller, Julie Yates, Jie Song, Chris Compton, Beulah Ji, Li Wu, Yang Yang, Paul Jones, Jinping Zheng
Published 2021-09-01

Risk assessment for hospital admission in patients with COPD; a multi-centre UK prospective observational study.

by Jilles M Fermont, Charlotte E Bolton, Marie Fisk, Divya Mohan, William Macnee, John R Cockcroft, Carmel McEniery, Jonathan Fuld, Joseph Cheriyan, Ruth Tal-Singer, Ian B Wilkinson, Angela M Wood, Michael I Polkey, Hana Müllerova
Published 2020-01-01

It’s more than low BMI: prevalence of cachexia and associated mortality in COPD

by Merry-Lynn N. McDonald, Emiel F. M. Wouters, Erica Rutten, Richard Casaburi, Stephen I. Rennard, David A. Lomas, Marcas Bamman, Bartolome Celli, Alvar Agusti, Ruth Tal-Singer, Craig P. Hersh, Mark Dransfield, Edwin K. Silverman
Published 2019-05-01

The p38 mitogen activated protein kinase inhibitor losmapimod in chronic obstructive pulmonary disease patients with systemic inflammation, stratified by fibrinogen: A randomised d...

by Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Kaisa M Mäki-Petäjä, Carmel M McEniery, Jonathan Fuld, James H F Rudd, Nicholas S Hopkinson, David A Lomas, John R Cockcroft, Ruth Tal-Singer, Michael I Polkey, Ian B Wilkinson
Published 2018-01-01

Quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography to assess pulmonary inflammation in COPD

by Laurence Vass, Marie Fisk, Joseph Cheriyan, Divya Mohan, Julia Forman, Adelola Oseni, Anand Devaraj, Kaisa M. Mäki-Petäjä, Carmel M. McEniery, Jonathan Fuld, Nicholas S. Hopkinson, David A. Lomas, John R. Cockcroft, Ruth Tal-Singer, Michael I. Polkey, Ian B. Wilkinson
Published 2021-08-01

Genetics of sputum gene expression in chronic obstructive pulmonary disease.

by Weiliang Qiu, Michael H Cho, John H Riley, Wayne H Anderson, Dave Singh, Per Bakke, Amund Gulsvik, Augusto A Litonjua, David A Lomas, James D Crapo, Terri H Beaty, Bartolome R Celli, Stephen Rennard, Ruth Tal-Singer, Steven M Fox, Edwin K Silverman, Craig P Hersh, ECLIPSE Investigators
Published 2011-01-01