Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes.

by Jamie L Ifkovits, Russell C Addis, Jonathan A Epstein, John D Gearhart
Published 2014-01-01

Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector.

by Russell C Addis, Fu-Chun Hsu, Rebecca L Wright, Marc A Dichter, Douglas A Coulter, John D Gearhart
Published 2011-01-01

Transcription factors MYOCD, SRF, Mesp1 and SMARCD3 enhance the cardio-inducing effect of GATA4, TBX5, and MEF2C during direct cellular reprogramming.

by Nicolas Christoforou, Malathi Chellappan, Andrew F Adler, Robert D Kirkton, Tianyi Wu, Russell C Addis, Nenad Bursac, Kam W Leong
Published 2013-01-01