In vitro cytochrome P450‐ and transporter‐mediated drug interaction potential of 6β‐hydroxy‐21‐desacetyl deflazacort—A major human metabolite of deflazacort

by Jiyuan Ma, Brian Beers, Ravi Manohar, Stephen Roe, Joseph M. Colacino, Ronald Kong
Published 2021-04-01

Metabolite V, an epoxide species is a minor circulating metabolite in humans following a single oral dose of deflazacort

by Ronald Kong, Jiyuan Ma, Brian Beers, Diksha Kaushik, E Lin, Elizabeth Goodwin, Joseph Colacino, Francesco Bibbiani
Published 2020-12-01

In vitro metabolism, reaction phenotyping, enzyme kinetics, CYP inhibition and induction potential of ataluren

by Ronald Kong, Jiyuan Ma, Seongwoo Hwang, Young‐Choon Moon, Ellen M. Welch, Marla Weetall, Joseph M. Colacino, Neil Almstead, John Babiak, Elizabeth Goodwin
Published 2020-04-01