Mice lacking NKT cells but with a complete complement of CD8+ T-cells are not protected against the metabolic abnormalities of diet-induced obesity.

by Benjamin S Mantell, Maja Stefanovic-Racic, Xiao Yang, Nikolas Dedousis, Ian J Sipula, Robert M O'Doherty
Published 2011-01-01

Bone marrow lympho-myeloid malfunction in obesity requires precursor cell-autonomous TLR4

by Ailing Liu, Minhui Chen, Rashmi Kumar, Maja Stefanovic-Racic, Robert M. O’Doherty, Ying Ding, Willi Jahnen-Dechent, Lisa Borghesi
Published 2018-02-01

Notch intracellular domain overexpression in adipocytes confers lipodystrophy in mice

by Dionysios V. Chartoumpekis, Dushani L. Palliyaguru, Nobunao Wakabayashi, Nicholas K.H. Khoo, Gabriele Schoiswohl, Robert M. O'Doherty, Thomas W. Kensler
Published 2015-07-01

Adropin reduces blood glucose levels in mice by limiting hepatic glucose production

by Dharendra Thapa, Bingxian Xie, Janet R. Manning, Manling Zhang, Michael W. Stoner, Brydie R. Huckestein, Lia R. Edmunds, Xueyang Zhang, Nikolaos L. Dedousis, Robert M. O'Doherty, Michael J. Jurczak, Iain Scott
Published 2019-04-01

DNA methylation alters transcriptional rates of differentially expressed genes and contributes to pathophysiology in mice fed a high fat diet

by Pili Zhang, Tianjiao Chu, N. Dedousis, Benjamin S. Mantell, Ian Sipula, Lucy Li, Kimberly D. Bunce, Patricia A. Shaw, Liora S. Katz, Jun Zhu, Carmen Argmann, Robert M. O'Doherty, David G. Peters, Donald K. Scott
Published 2017-04-01

Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance.

by Frances R Belmonte, Nikolaos Dedousis, Ian Sipula, Nikita A Desai, Aatur D Singhi, Yanxia Chu, Yingze Zhang, Sylvie Bannwarth, Véronique Paquis-Flucklinger, Lea Harrington, Sruti Shiva, Michael J Jurczak, Robert M O'Doherty, Brett A Kaufman
Published 2019-01-01