A novel SERPINA1 mutation causing serum alpha(1)-antitrypsin deficiency.

by Darren N Saunders, Elizabeth A Tindall, Robert F Shearer, Jacquelyn Roberson, Amy Decker, Jean Amos Wilson, Vanessa M Hayes
Published 2012-01-01

Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate‐induced apoptosis

by Seher Balaban, Lisa S. Lee, Bianca Varney, Atqiya Aishah, Quanqing Gao, Robert F. Shearer, Darren N. Saunders, Thomas Grewal, Andrew J. Hoy
Published 2018-09-01

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation.

by Jodi A Lee, Justin J Yerbury, Natalie Farrawell, Robert F Shearer, Patrick Constantinescu, Danny M Hatters, Wayne A Schroder, Andreas Suhrbier, Mark R Wilson, Darren N Saunders, Marie Ranson
Published 2015-01-01

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer

by Sean P. Kennedy, Jeremy Z. R. Han, Neil Portman, Max Nobis, Jordan F. Hastings, Kendelle J. Murphy, Sharissa L. Latham, Antonia L. Cadell, Dushan Miladinovic, Gabriella R. Marriott, Yolande E. I. O’Donnell, Robert F. Shearer, James T. Williams, Amaya Garcia Munoz, Thomas R. Cox, D. Neil Watkins, Darren N. Saunders, Paul Timpson, Elgene Lim, Walter Kolch, David R. Croucher
Published 2019-03-01

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

by James R.W. Conway, Sean C. Warren, David Herrmann, Kendelle J. Murphy, Aurélie S. Cazet, Claire Vennin, Robert F. Shearer, Monica J. Killen, Astrid Magenau, Pauline Mélénec, Mark Pinese, Max Nobis, Anaiis Zaratzian, Alice Boulghourjian, Andrew M. Da Silva, Gonzalo del Monte-Nieto, Arne S.A. Adam, Richard P. Harvey, Jody J. Haigh, Yingxiao Wang, David R. Croucher, Owen J. Sansom, Marina Pajic, C. Elizabeth Caldon, Jennifer P. Morton, Paul Timpson
Published 2018-06-01