Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes

by Jiajia Wang, Q. Richard Lu
Published 2020-10-01

Epigenetic regulation of oligodendrocyte myelination in developmental disorders and neurodegenerative diseases [version 1; peer review: 2 approved]

by Kalen Berry, Jiajia Wang, Q. Richard Lu
Published 2020-02-01

PRICING THE REVENUE INSURANCE OF SUGAR APPLE AND BANANA IN TAIWAN: AN ACTUARIAL APPROACH

by Min-Hsien Yang, Richard Lu, Matt Lin, Nian-Zu Yao
Published 2021-04-01

Leanness and Low Plasma Leptin in GPR17 Knockout Mice Are Dependent on Strain and Associated With Increased Energy Intake That Is Not Suppressed by Exogenous Leptin

by Edward T. Wargent, Suhaib J. S. Ahmad, Qing Richard Lu, Evi Kostenis, Jonathan R. S. Arch, Claire J. Stocker
Published 2021-09-01

Activation of oligodendroglial Stat3 is required for efficient remyelination

by Andrew J. Steelman, Yun Zhou, Hisami Koito, SunJa Kim, H. Ross Payne, Q. Richard Lu, Jianrong Li
Published 2016-07-01

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

by Richard Lu, Bobby Brooke Herrera, Heather D Eshleman, Yang Fu, Alexander Bloom, Zhigang Li, David B Sacks, Marcia B Goldberg
Published 2015-10-01

Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes

by Minqing Jiang, Lei Liu, Xuelian He, Haibo Wang, Wensheng Lin, Huimin Wang, Sung O. Yoon, Teresa L. Wood, Q. Richard Lu
Published 2016-07-01

Correction: Corrigendum: Regulation of PERK–eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes

by Minqing Jiang, Lei Liu, Xuelian He, Haibo Wang, Wensheng Lin, Huimin Wang, Sung O Yoon, Teresa L Wood, Q. Richard Lu
Published 2016-11-01

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

by Qinjie Weng, Jiajia Wang, Jiaying Wang, Biqin Tan, Jing Wang, Haibo Wang, Tao Zheng, Q. Richard Lu, Bo Yang, Qiaojun He
Published 2017-05-01

CTCF-mediated chromatin looping in EGR2 regulation and SUZ12 recruitment critical for peripheral myelination and repair

by Jincheng Wang, Jiajia Wang, Lijun Yang, Chuntao Zhao, Laiman Natalie Wu, Lingli Xu, Feng Zhang, Qinjie Weng, Michael Wegner, Q. Richard Lu
Published 2020-08-01

A reciprocal regulatory loop between TAZ/YAP and G-protein Gαs regulates Schwann cell proliferation and myelination

by Yaqi Deng, Lai Man Natalie Wu, Shujun Bai, Chuntao Zhao, Haibo Wang, Jincheng Wang, Lingli Xu, Masahide Sakabe, Wenhao Zhou, Mei Xin, Q. Richard Lu
Published 2017-04-01

A GPR17-cAMP-Lactate Signaling Axis in Oligodendrocytes Regulates Whole-Body Metabolism

by Zhimin Ou, Yanchen Ma, Yuxia Sun, Gege Zheng, Shiyun Wang, Rui Xing, Xiang Chen, Ying Han, Jiajia Wang, Q. Richard Lu, Tong-Jin Zhao, Ying Chen
Published 2019-03-01

Deletion of SMARCA4 impairs alveolar epithelial type II cells proliferation and aggravates pulmonary fibrosis in mice

by Danyi Peng, Daozhu Si, Rong Zhang, Jiang Liu, Hao Gou, Yunqiu Xia, Daiyin Tian, Jihong Dai, Ke Yang, Enmei Liu, Yujun Shi, Q. Richard Lu, Lin Zou, Zhou Fu
Published 2017-12-01

The Chromatin Environment Around Interneuron Genes in Oligodendrocyte Precursor Cells and Their Potential for Interneuron Reprograming

by Linda L. Boshans, Linda L. Boshans, Daniel C. Factor, Vijender Singh, Jia Liu, Chuntao Zhao, Ion Mandoiu, Q. Richard Lu, Patrizia Casaccia, Paul J. Tesar, Akiko Nishiyama, Akiko Nishiyama, Akiko Nishiyama
Published 2019-08-01

Genomic and Transcriptomic Analyses Reveals ZNF124 as a Critical Regulator in Highly Aggressive Medulloblastomas

by Zaili Luo, Xinran Dong, Jianzhong Yu, Yong Xia, Kalen P. Berry, Rohit Rao, Lingli Xu, Ping Xue, Tong Chen, Yifeng Lin, Jiyang Yu, Guoying Huang, Hao Li, Wenhao Zhou, Q. Richard Lu
Published 2021-02-01

MYRF is a membrane-associated transcription factor that autoproteolytically cleaves to directly activate myelin genes.

by Helena Bujalka, Matthias Koenning, Stacey Jackson, Victoria M Perreau, Bernard Pope, Curtis M Hay, Stanlislaw Mitew, Andrew F Hill, Q Richard Lu, Michael Wegner, Rajini Srinivasan, John Svaren, Melanie Willingham, Ben A Barres, Ben Emery
Published 2013-01-01

Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region

by Wei Liu, Hui Zhou, Lei Liu, Chuntao Zhao, Yaqi Deng, Lina Chen, Laiman Wu, Nicole Mandrycky, Christopher T. McNabb, Yuanbo Peng, Perry N. Fuchs, Jie Lu, Volney Sheen, Mengsheng Qiu, Meng Mao, Q. Richard Lu
Published 2015-05-01

Ten-eleven translocation 1 mediated-DNA hydroxymethylation is required for myelination and remyelination in the mouse brain

by Ming Zhang, Jian Wang, Kaixiang Zhang, Guozhen Lu, Yuming Liu, Keke Ren, Wenting Wang, Dazhuan Xin, Lingli Xu, Honghui Mao, Junlin Xing, Xingchun Gao, Weilin Jin, Kalen Berry, Katsuhiko Mikoshiba, Shengxi Wu, Q. Richard Lu, Xianghui Zhao
Published 2021-08-01

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

by Chuntao Zhao, Yaqi Deng, Lei Liu, Kun Yu, Liguo Zhang, Haibo Wang, Xuelian He, Jincheng Wang, Changqing Lu, Laiman N Wu, Qinjie Weng, Meng Mao, Jianrong Li, Johan H van Es, Mei Xin, Lee Parry, Steven A Goldman, Hans Clevers, Q. Richard Lu
Published 2016-03-01

The Transcriptional Activator Krüppel-like Factor-6 Is Required for CNS Myelination.

by Benjamin M Laitman, Linnéa Asp, John N Mariani, Jingya Zhang, Jia Liu, Setsu Sawai, Candice Chapouly, Sam Horng, Elisabeth G Kramer, Nesanet Mitiku, Hannah Loo, Natalie Burlant, Xiomara Pedre, Yuko Hara, German Nudelman, Elena Zaslavsky, Young-Min Lee, David A Braun, Q Richard Lu, Goutham Narla, Cedric S Raine, Scott L Friedman, Patrizia Casaccia, Gareth R John
Published 2016-05-01