Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma.

by Kinga A Kocemba, Richard W J Groen, Harmen van Andel, Marie José Kersten, Karène Mahtouk, Marcel Spaargaren, Steven T Pals
Published 2012-01-01

Polymeric micelles loaded with carfilzomib increase tolerability in a humanized bone marrow-like scaffold mouse model

by Aida Varela-Moreira, Demian van Straten, Heleen F. van Leur, Ruud W.J. Ruiter, Anil K. Deshantri, Wim E. Hennink, Marcel H.A.M. Fens, Richard W.J. Groen, Raymond M. Schiffelers
Published 2020-12-01

Bone Marrow Mesenchymal Stromal Cell-mediated Resistance in Multiple Myeloma Against NK Cells can be Overcome by Introduction of CD38-CAR or TRAIL-variant

by Lisa C. Holthof, Arwen Stikvoort, Hilma J. van der Horst, Anne T. Gelderloos, Renée Poels, Fengzhi Li, Richard W. J. Groen, Sonja Zweegman, Niels W. C. J. van de Donk, Michael O’Dwyer, Tuna Mutis
Published 2021-05-01

Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis

by Vincent van den Boom, Henny Maat, Marjan Geugien, Aida Rodríguez López, Ana M. Sotoca, Jennifer Jaques, Annet Z. Brouwers-Vos, Fabrizia Fusetti, Richard W.J. Groen, Huipin Yuan, Anton C.M. Martens, Hendrik G. Stunnenberg, Edo Vellenga, Joost H.A. Martens, Jan Jacob Schuringa
Published 2016-01-01

Complete Tumor Regression by Liposomal Bortezomib in a Humanized Mouse Model of Multiple Myeloma

by Anil K. Deshantri, Marcel H.A.M. Fens, Ruud W.J. Ruiter, Josbert M. Metselaar, Gert Storm, Sanjay N. Mandhane, Gerard H.M. Graat, Eef G.W. Lentjes, Huipin Yuan, Joost D. de Bruijn, Tuna Mutis, Anton C.M. Martens, Richard W.J. Groen, Raymond M. Schiffelers
Published 2020-10-01