Immunopathological basis of immune-related adverse events induced by immune checkpoint blockade therapy

by Terufumi Kubo, Yoshihiko Hirohashi, Tomohide Tsukahara, Takayuki Kanaseki, Kenji Murata, Rena Morita, Toshihiko Torigoe
Published 2021-09-01

ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosis.

by Takafumi Kuroda, Yoshihiko Hirohashi, Toshihiko Torigoe, Kazuyo Yasuda, Akari Takahashi, Hiroko Asanuma, Rena Morita, Tasuku Mariya, Takuya Asano, Masahito Mizuuchi, Tsuyoshi Saito, Noriyuki Sato
Published 2013-01-01

Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.

by Kazuyo Yasuda, Toshihiko Torigoe, Rena Morita, Takahumi Kuroda, Akari Takahashi, Junichi Matsuzaki, Vitaly Kochin, Hiroko Asanuma, Tadashi Hasegawa, Tsuyoshi Saito, Yoshihiko Hirohashi, Noriyuki Sato
Published 2013-01-01

Non‐bacterial cystitis with increased expression of programmed death‐ligand 1 in the urothelium: An unusual immune‐related adverse event during treatment with pembrolizumab for lun...

by Yohei Ueki, Masahiro Matsuki, Terufumi Kubo, Rena Morita, Yoshihiko Hirohashi, Syunsuke Sato, Ryota Horibe, Kazuhiko Matsuo, Tomohide Tsukahara, Takayuki Kanaseki, Yasunari Takakuwa, Masaaki Satoh, Naoki Itoh, Toshihiko Torigoe
Published 2020-11-01

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.

by Akari Takaya, Yoshihiko Hirohashi, Aiko Murai, Rena Morita, Hiroshi Saijo, Eri Yamamoto, Terufumi Kubo, Munehide Nakatsugawa, Takayuki Kanaseki, Tomohide Tsukahara, Yasuaki Tamura, Ichiro Takemasa, Toru Kondo, Noriyuki Sato, Toshihiko Torigoe
Published 2016-01-01

Fatal fulminant hepatitis induced by combined ipilimumab and nivolumab therapy despite favorable histologic response and confirmed by autopsy in a patient with clear cell renal cel...

by Terufumi Kubo, Taro Sugawara, Tomoyo Shinkawa, Tomoyo Kurisu, Nodoka Kouzen, Toshiaki Tanaka, Fumimasa Fukuta, Kouji Yamasaki, Shintaro Sugita, Kazuhiko Matsuo, Rena Morita, Yoshihiko Hirohashi, Tomohide Tsukahara, Takayuki Kanaseki, Tadashi Hasegawa, Naoya Masumori, Toshihiko Torigoe
Published 2021-04-01