Exploiting synthetic lethal interactions for targeted cancer therapy

by Reinhardt, H. Christian, Jiang, Hai, Hemann, Michael, Yaffe, Michael B
Published 2012

A Reversible Gene-Targeting Strategy Identifies Synthetic Lethal Interactions between MK2 and p53 in the DNA Damage Response In Vivo

by Reinhardt, H. Christian, Kim, Jacob S, Ruf, Daniela M, Mitra, Tanya, Couvillon, Anthony D, Yaffe, Michael B, Cannell, Ian Gordon, Reinhardt, H. Christian, Kim, Jacob S., Ruf, Daniela M., Morandell, Sandra M., Jacks, Tyler E, Yaffe, Michael B
Published 2014

DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization

by Reinhardt, H. Christian, Hasskamp, Pia, Schmedding, Ingolf, Morandell, Sandra, van Vugt, Marcel A.T.M, Wang, XiaoZhe, Linding, Rune, Ong, Shao-En, Weaver, David, Carr, Steven A., Yaffe, Michael B
Published 2014

Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints

by Kong, Yi Wen, Dreaden, Erik C, Morandell, Sandra, Zhou, Wen, Dhara, Sanjeev S, Sriram, Ganapathy, Lam, Fred C, Patterson, Jesse C, Quadir, Mohiuddin, Dinh, Anh, Shopsowitz, Kevin E, Varmeh, Shohreh, Yilmaz, Ömer H, Lippard, Stephen J, Reinhardt, H Christian, Hemann, Michael T, Hammond, Paula T, Yaffe, Michael B
Published 2021