Immunogenic, but not steady-state, antigen presentation permits regulatory T-cells to control CD8+ T-cell effector differentiation by IL-2 modulation.

by Alice McNally, Michael McNally, Ryan Galea, Ranjeny Thomas, Raymond J Steptoe
Published 2014-01-01

Blockade of PD-1/PD-L1 promotes adoptive T-cell immunotherapy in a tolerogenic environment.

by Stephen J P Blake, Alan L H Ching, Tony J Kenna, Ryan Galea, Justin Large, Hideo Yagita, Raymond J Steptoe
Published 2015-01-01

Clinically-Relevant Rapamycin Treatment Regimens Enhance CD8+ Effector Memory T Cell Function In The Skin and Allow their Infiltration into Cutaneous Squamous Cell Carcinoma

by Ji-Won Jung, Margaret Veitch, Jennifer A. Bridge, Nana H. Overgaard, Jazmina L. Cruz, Richard Linedale, Michael E. Franklin, Nicholas A. Saunders, Fiona Simpson, Ian H. Frazer, Raymond J. Steptoe, James W. Wells
Published 2018-09-01

HMGB1 amplifies ILC2-induced type-2 inflammation and airway smooth muscle remodelling.

by Zhixuan Loh, Jennifer Simpson, Ashik Ullah, Vivian Zhang, Wan J Gan, Jason P Lynch, Rhiannon B Werder, Al Amin Sikder, Katie Lane, Choon Boon Sim, Enzo Porrello, Stuart B Mazzone, Peter D Sly, Raymond J Steptoe, Kirsten M Spann, Maria B Sukkar, John W Upham, Simon Phipps
Published 2020-07-01

Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling

by Jessica C. Kling, Margaret A. Jordan, Lauren A. Pitt, Jana Meiners, Thao Thanh-Tran, Le Son Tran, Tam T. K. Nguyen, Deepak Mittal, Rehan Villani, Raymond J. Steptoe, Kiarash Khosrotehrani, Stuart P. Berzins, Stuart P. Berzins, Alan G. Baxter, Dale I. Godfrey, Dale I. Godfrey, Antje Blumenthal
Published 2018-03-01