Covalent Bonding of Pyrrolobenzodiazepines (PBDs) to Terminal Guanine Residues within Duplex and Hairpin DNA Fragments.

by Julia Mantaj, Paul J M Jackson, Kersti Karu, Khondaker M Rahman, David E Thurston
Published 2016-01-01

Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes.

by Khondaker M Rahman, David B Corcoran, Tam T T Bui, Paul J M Jackson, David E Thurston
Published 2014-01-01

A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma

by Ricarda M. Hoffmann, Silvia Crescioli, Silvia Mele, Eirini Sachouli, Anthony Cheung, Connie K. Chui, Paolo Andriollo, Paul J. M. Jackson, Katie E. Lacy, James F. Spicer, David E. Thurston, Sophia N. Karagiannis
Published 2020-04-01