Critical role of post-transcriptional regulation for IFN-γ in tumor-infiltrating T cells

by Fiamma Salerno, Aurelie Guislain, Julian J. Freen-Van Heeren, Benoit P. Nicolet, Howard A. Young, Monika C. Wolkers
Published 2019-02-01

Adrenergic β2 receptor activation stimulates anti-inflammatory properties of dendritic cells in vitro.

by Laurens E Nijhuis, Brenda J Olivier, Shobit Dhawan, Francisca W Hilbers, Louis Boon, Monika C Wolkers, Janneke N Samsom, Wouter J de Jonge
Published 2014-01-01

Enhanced CD8 T cell responses through GITR-mediated costimulation resolve chronic viral infection.

by Maria Fernanda Pascutti, Sulima Geerman, Edith Slot, Klaas P J M van Gisbergen, Louis Boon, Ramon Arens, Rene A W van Lier, Monika C Wolkers, Martijn A Nolte
Published 2015-03-01

Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine

by Krijn K. Dijkstra, Kim Monkhorst, Luuk J. Schipper, Koen J. Hartemink, Egbert F. Smit, Sovann Kaing, Rosa de Groot, Monika C. Wolkers, Hans Clevers, Edwin Cuppen, Emile E. Voest
Published 2020-05-01

m6A methylation potentiates cytosolic dsDNA recognition in a sequence-specific manner

by Melania Balzarolo, Sander Engels, Anja J. de Jong, Katka Franke, Timo K. van den Berg, Muhammet F. Gulen, Andrea Ablasser, Edith M. Janssen, Bas van Steensel, Monika C. Wolkers
Published 2021-03-01

T cells expanded from renal cell carcinoma display tumor-specific CD137 expression but lack significant IFN-γ, TNF-α or IL-2 production

by Saskia D. van Asten, Rosa de Groot, Marleen M. van Loenen, Suzanne M. Castenmiller, Jeroen de Jong, Kim Monkhorst, John B.A.G. Haanen, Derk Amsen, Axel Bex, Robbert M. Spaapen, Monika C. Wolkers
Published 2021-01-01

Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile

by Rosa De Groot, Marleen M. Van Loenen, Aurélie Guislain, Benoît P. Nicolet, Julian J. Freen-Van Heeren, Onno J.H.M. Verhagen, Michel M. Van Den Heuvel, Jeroen De Jong, Patrick Burger, C.Ellen Van Der Schoot, Robbert M. Spaapen, Derk Amsen, John B. A. G. Haanen, Kim Monkhorst, Koen J. Hartemink, Monika C. Wolkers
Published 2019-11-01