Mitochondria-Targeted Antioxidants MitoQ and MitoTEMPO Do Not Influence BRAF-Driven Malignant Melanoma and KRAS-Driven Lung Cancer Progression in Mice

by Kristell Le Gal, Clotilde Wiel, Mohamed X. Ibrahim, Marcus Henricsson, Volkan I. Sayin, Martin O. Bergo
Published 2021-01-01

Zfp148 deficiency causes lung maturation defects and lethality in newborn mice that are rescued by deletion of p53 or antioxidant treatment.

by Volkan I Sayin, Anna Nilton, Mohamed X Ibrahim, Pia Ågren, Erik Larsson, Marleen M Petit, Lillemor Mattsson Hultén, Marcus Ståhlman, Bengt R Johansson, Martin O Bergo, Per Lindahl
Published 2013-01-01

A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

by Xue Chen, Haidong Yao, Muhammad Kashif, Gwladys Revêchon, Maria Eriksson, Jianjiang Hu, Ting Wang, Yiran Liu, Elin Tüksammel, Staffan Strömblad, Ian M Ahearn, Mark R Philips, Clotilde Wiel, Mohamed X Ibrahim, Martin O Bergo
Published 2021-02-01

Protein prenylation restrains innate immunity by inhibiting Rac1 effector interactions

by Murali K. Akula, Mohamed X. Ibrahim, Emil G. Ivarsson, Omar M. Khan, Israiel T. Kumar, Malin Erlandsson, Christin Karlsson, Xiufeng Xu, Mikael Brisslert, Cord Brakebusch, Donghai Wang, Maria Bokarewa, Volkan I. Sayin, Martin O. Bergo
Published 2019-09-01

Antioxidants Promote Intestinal Tumor Progression in Mice

by Zhiyuan V. Zou, Kristell Le Gal, Ahmed E. El Zowalaty, Lara E. Pehlivanoglu, Viktor Garellick, Nadia Gul, Mohamed X. Ibrahim, Per-Olof Bergh, Marcus Henricsson, Clotilde Wiel, Levent M. Akyürek, Martin O. Bergo, Volkan I. Sayin, Per Lindahl
Published 2021-02-01