Inhibition of TGF-β signaling enables human corneal endothelial cell expansion in vitro for use in regenerative medicine.

by Naoki Okumura, EunDuck P Kay, Makiko Nakahara, Junji Hamuro, Shigeru Kinoshita, Noriko Koizumi
Published 2013-01-01

Cultivation of corneal endothelial cells on a pericellular matrix prepared from human decidua-derived mesenchymal cells.

by Ryohei Numata, Naoki Okumura, Makiko Nakahara, Morio Ueno, Shigeru Kinoshita, Daisuke Kanematsu, Yonehiro Kanemura, Yoshiki Sasai, Noriko Koizumi
Published 2014-01-01

Corneal endothelial expansion promoted by human bone marrow mesenchymal stem cell-derived conditioned medium.

by Makiko Nakahara, Naoki Okumura, EunDuck P Kay, Michio Hagiya, Kiwamu Imagawa, Yuuki Hosoda, Shigeru Kinoshita, Noriko Koizumi
Published 2013-01-01

Generation and Feasibility Assessment of a New Vehicle for Cell-Based Therapy for Treating Corneal Endothelial Dysfunction.

by Naoki Okumura, Kazuya Kakutani, Ryota Inoue, Daiki Matsumoto, Tomoki Shimada, Makiko Nakahara, Yumiko Kiyanagi, Takehiro Itoh, Noriko Koizumi
Published 2016-01-01

Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy

by Naoki Okumura, Keisuke Hashimoto, Miu Kitahara, Hirokazu Okuda, Emi Ueda, Kyoko Watanabe, Makiko Nakahara, Takahiko Sato, Shigeru Kinoshita, Theofilos Tourtas, Ursula Schlötzer-Schrehardt, Friedrich Kruse, Noriko Koizumi
Published 2017-07-01