Acidic stress Acidosis Adaptation, Physiological Autophagy Carcinoma, Pancreatic Ductal Cell Line, Tumor Extracellular pH Fission Fusion Gene Expression Regulation, Neoplastic Humans Hydrogen-Ion Concentration Mitochondrial dynamics Pancreatic Ducts Pancreatic Neoplasms Pancreatic ductal adenocarcinoma Tumor Microenvironment Tumor microenvironment acidosis adaptation gene expression regulation genetics human metabolism pH pancreas carcinoma pancreas tumor pancreatic duct pathology tumor cell line