Dipotassium N-stearoyltyrosinate ameliorated pathological injuries in triple-transgenic mouse model of Alzheimer's disease

by Sha Liu, Shuang-Qi Tang, Heng-Jing Cui, Sha Yin, Ming Yin, Hong Zhao, Ling-Hua Meng, Ze-Jian Wang, Yang Lu
Published 2016-09-01

PI3Kα inhibitor CYH33 triggers antitumor immunity in murine breast cancer by activating CD8+T cells and promoting fatty acid metabolism

by Xi Zhang, Yi Wang, Jian Ding, Lan Xu, Pu Sun, Rong-Jing Wang, Qing-Yang Ma, Hui-Ping Liao, Hai-Long Wang, Lan-Dian Hu, Xiangyin Kong, Ling-Hua Meng
Published 2021-08-01

Adaptive resistance to PI3Kα-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells

by Yu-xiang Wang, Xu Zhang, Qing-yang Ma, Lan-dian Hu, Xi Zhang, Yi Wang, Lan Xu, Chun-hao Yang, Cun Tan, Xiang-yin Kong, Jian Ding, Ling-hua Meng
Published 2021-01-01

S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.

by Chao Zhang, Na Yang, Chun-Hao Yang, Hua-Sheng Ding, Cheng Luo, Yu Zhang, Mao-Jiang Wu, Xiong-Wen Zhang, Xu Shen, Hua-Liang Jiang, Ling-Hua Meng, Jian Ding
Published 2009-01-01