Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype.

by Diana Gabriel, Leslie B Gordon, Karima Djabali
Published 2016-01-01

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin.

by Dayle McClintock, Desiree Ratner, Meepa Lokuge, David M Owens, Leslie B Gordon, Francis S Collins, Karima Djabali
Published 2007-12-01

Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

by Vera Wenzel, Daniela Roedl, Diana Gabriel, Leslie B. Gordon, Meenhard Herlyn, Reinhard Schneider, Johannes Ring, Karima Djabali
Published 2012-04-01

Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition.

by Jackleen Marji, Seán I O'Donoghue, Dayle McClintock, Venkata P Satagopam, Reinhard Schneider, Desiree Ratner, Howard J Worman, Leslie B Gordon, Karima Djabali
Published 2010-06-01