Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains

by Eilis Hannon, Sarah J. Marzi, Leonard S. Schalkwyk, Jonathan Mill
Published 2019-01-01

5-hydroxymethylcytosine is highly dynamic across human fetal brain development

by Helen Spiers, Eilis Hannon, Leonard C. Schalkwyk, Nicholas J. Bray, Jonathan Mill
Published 2017-09-01

To what extent is blood a reasonable surrogate for brain in gene expression studies: estimation from mouse hippocampus and spleen

by Matthew N Davies, Sarah Lawn, Steven Whatley, Cathy Fernandes, Robert W Williams, Leonard C Schalkwyk
Published 2009-10-01

Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array

by Georgina Mansell, Tyler J. Gorrie-Stone, Yanchun Bao, Meena Kumari, Leonard S. Schalkwyk, Jonathan Mill, Eilis Hannon
Published 2019-05-01

Advancing paternal age is associated with deficits in social and exploratory behaviors in the offspring: a mouse model.

by Rebecca G Smith, Rachel L Kember, Jonathan Mill, Cathy Fernandes, Leonard C Schalkwyk, Joseph D Buxbaum, Abraham Reichenberg
Published 2009-01-01

Peripheral blood RNA gene expression profiling in patients with bacterial meningitis

by Margit eLill, Pille eTaba, Sulev eKõks, Ursel eSoomets, Irja eLutsar, Leonard C Schalkwyk, Cathy eFernandes
Published 2013-03-01

RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation

by Ayden Saffari, Matt Arno, Eric Nasser, Angelica Ronald, Chloe C. Y. Wong, Leonard C. Schalkwyk, Jonathan Mill, Frank Dudbridge, Emma L. Meaburn
Published 2019-11-01

Effect of Chronic Valproic Acid Treatment on Hepatic Gene Expression Profile in Wfs1 Knockout Mouse

by Marite Punapart, Mall Eltermaa, Julia Oflijan, Silva Sütt, Anne Must, Sulev Kõks, Leonard C. Schalkwyk, Catherine Fernandes, Eero Vasar, Ursel Soomets, Anton Terasmaa
Published 2014-01-01

Reduced anxiety and depression-like behaviours in the circadian period mutant mouse afterhours.

by Robert Keers, Inti Pedroso, Gerome Breen, Kathy J Aitchison, Patrick M Nolan, Sven Cichon, Markus M Nöthen, Marcella Rietschel, Leonard C Schalkwyk, Cathy Fernandes
Published 2012-01-01

DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

by Yucheng Wang, Eilis Hannon, Olivia A. Grant, Tyler J. Gorrie-Stone, Meena Kumari, Jonathan Mill, Xiaojun Zhai, Klaus D. McDonald-Maier, Leonard C. Schalkwyk
Published 2021-06-01

Systematic underestimation of the epigenetic clock and age acceleration in older subjects

by Louis Y. El Khoury, Tyler Gorrie-Stone, Melissa Smart, Amanda Hughes, Yanchun Bao, Alexandria Andrayas, Joe Burrage, Eilis Hannon, Meena Kumari, Jonathan Mill, Leonard C. Schalkwyk
Published 2019-12-01

The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations.

by Fredrika Åsenius, Tyler J Gorrie-Stone, Ama Brew, Yasmin Panchbhaya, Elizabeth Williamson, Leonard C Schalkwyk, Vardhman K Rakyan, Michelle L Holland, Sarah J Marzi, David J Williams
Published 2020-10-01

Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients.

by Timothy R Powell, Peter McGuffin, Ursula M D'Souza, Sarah Cohen-Woods, Georgina M Hosang, Charlotte Martin, Keith Matthews, Richard K Day, Anne E Farmer, Katherine E Tansey, Leonard C Schalkwyk
Published 2014-01-01

Genetics of the hippocampal transcriptome in mouse: a systematic survey and online neurogenomics resource

by Rupert W Overall, Gerd Kempermann, Jeremy Peirce, Lu Lu, Dan Goldowitz, Fred H Gage, Shirlean Goodwin, August B Smit, David C Airey, Glenn D Rosen, Leonard C Schalkwyk, Thomas R Sutter, Richard S. Nowakowski, Stephen Whatley, Robert W Williams
Published 2009-11-01

Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

by Lotte C. Houtepen, Christiaan H. Vinkers, Tania Carrillo-Roa, Marieke Hiemstra, Pol A. van Lier, Wim Meeus, Susan Branje, Christine M. Heim, Charles B. Nemeroff, Jonathan Mill, Leonard C. Schalkwyk, Menno P. Creyghton, René S. Kahn, Marian Joëls, Elisabeth B. Binder, Marco P. M. Boks
Published 2016-03-01

Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

by Heath E. O’Brien, Eilis Hannon, Matthew J. Hill, Carolina C. Toste, Matthew J. Robertson, Joanne E. Morgan, Gemma McLaughlin, Cathryn M. Lewis, Leonard C. Schalkwyk, Lynsey S. Hall, Antonio F. Pardiñas, Michael J. Owen, Michael C. O’Donovan, Jonathan Mill, Nicholas J. Bray
Published 2018-11-01

DNA methylation aging clocks: challenges and recommendations

by Christopher G. Bell, Robert Lowe, Peter D. Adams, Andrea A. Baccarelli, Stephan Beck, Jordana T. Bell, Brock C. Christensen, Vadim N. Gladyshev, Bastiaan T. Heijmans, Steve Horvath, Trey Ideker, Jean-Pierre J. Issa, Karl T. Kelsey, Riccardo E. Marioni, Wolf Reik, Caroline L. Relton, Leonard C. Schalkwyk, Andrew E. Teschendorff, Wolfgang Wagner, Kang Zhang, Vardhman K. Rakyan
Published 2019-11-01

DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia

by Eilis Hannon, Emma L Dempster, Georgina Mansell, Joe Burrage, Nick Bass, Marc M Bohlken, Aiden Corvin, Charles J Curtis, David Dempster, Marta Di Forti, Timothy G Dinan, Gary Donohoe, Fiona Gaughran, Michael Gill, Amy Gillespie, Cerisse Gunasinghe, Hilleke E Hulshoff, Christina M Hultman, Viktoria Johansson, René S Kahn, Jaakko Kaprio, Gunter Kenis, Kaarina Kowalec, James MacCabe, Colm McDonald, Andrew McQuillin, Derek W Morris, Kieran C Murphy, Colette J Mustard, Igor Nenadic, Michael C O'Donovan, Diego Quattrone, Alexander L Richards, Bart PF Rutten, David St Clair, Sebastian Therman, Timothea Toulopoulou, Jim Van Os, John L Waddington, Wellcome Trust Case Control Consortium (WTCCC), CRESTAR consortium, Patrick Sullivan, Evangelos Vassos, Gerome Breen, David Andrew Collier, Robin M Murray, Leonard S Schalkwyk, Jonathan Mill
Published 2021-02-01