Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions

by Lauren C. Fleischer, H. Trent Spencer, Sunil S. Raikar
Published 2019-12-01

Non-signaling Chimeric Antigen Receptors Enhance Antigen-Directed Killing by γδ T Cells in Contrast to αβ T Cells

by Lauren C. Fleischer, Scott A. Becker, Rebecca E. Ryan, Andrew Fedanov, Christopher B. Doering, H. Trent Spencer
Published 2020-09-01

Ex vivo expanded patient-derived γδ T-cell immunotherapy enhances neuroblastoma tumor regression in a murine model

by Jaquelyn T. Zoine, Kristopher A. Knight, Lauren C. Fleischer, Kathryn S. Sutton, Kelly C. Goldsmith, Christopher B. Doering, H. Trent Spencer
Published 2019-08-01

Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines

by Sunil S. Raikar, Lauren C. Fleischer, Robert Moot, Andrew Fedanov, Na Yoon Paik, Kristopher A. Knight, Christopher B. Doering, H. Trent Spencer
Published 2018-03-01