Screening of a Focused Ubiquitin-Proteasome Pathway Inhibitor Library Identifies Small Molecules as Novel Modulators of Botulinum Neurotoxin Type A Toxicity

by Edanur Sen, Krishna P. Kota, Rekha G. Panchal, Sina Bavari, Erkan Kiris
Published 2021-09-01

Protein Kinase R Degradation Is Essential for Rift Valley Fever Virus Infection and Is Regulated by SKP1-CUL1-F-box (SCF)FBXW11-NSs E3 Ligase.

by Rajini Mudhasani, Julie P Tran, Cary Retterer, Krishna P Kota, Chris A Whitehouse, Sina Bavari
Published 2016-02-01

High content image-based screening of a protease inhibitor library reveals compounds broadly active against Rift Valley fever virus and other highly pathogenic RNA viruses.

by Rajini Mudhasani, Krishna P Kota, Cary Retterer, Julie P Tran, Chris A Whitehouse, Sina Bavari
Published 2014-08-01

High Content Image Based Analysis Identifies Cell Cycle Inhibitors as Regulators of Ebola Virus Infection

by Sina Bavari, Rekha G. Panchal, Julie P. Tran, Rajini Mudhasani, Cary Retterer, Jacqueline G. Benko, Krishna P. Kota
Published 2012-09-01

Integrating high-content imaging and chemical genetics to probe host cellular pathways critical for Yersinia pestis infection.

by Krishna P Kota, Brett Eaton, Douglas Lane, Melanie Ulrich, Ricky Ulrich, Brian D Peyser, Camenzind G Robinson, James G Jaissle, Gianluca Pegoraro, Sina Bavari, Rekha G Panchal
Published 2013-01-01

Alveolar macrophages infected with Ames or Sterne strain of Bacillus anthracis elicit differential molecular expression patterns.

by Felicia D Langel, Chih-Yuan Chiang, Douglas Lane, Tara Kenny, Jenifer F Ojeda, Yang Zhong, Jianwei Che, Yingyao Zhou, Wilson Ribot, Krishna P Kota, Sina Bavari, Rekha G Panchal
Published 2014-01-01

A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection

by Chih-Yuan eChiang, Ijeoma eUzoma, Douglas eLane, Vesna eMemišević, Farhang eAlem, Kuan eYao, Krishna P Kota, Sina eBavari, Anders eWallqvist, Ramin eHakami, Rekha ePanchal
Published 2015-07-01

Multi-faceted proteomic characterization of host protein complement of Rift Valley fever virus virions and identification of specific heat shock proteins, including HSP90, as impor...

by Jonathan E Nuss, Kylene Kehn-Hall, Ashwini Benedict, Julie Costantino, Michael Ward, Brian D Peyser, Cary J Retterer, Lyal E Tressler, Laura M Wanner, Hugh F McGovern, Anum Zaidi, Scott M Anthony, Krishna P Kota, Sina Bavari, Ramin M Hakami
Published 2014-01-01