Myeloid Cells in the Tumor Microenvironment: Modulation of Tumor Angiogenesis and Tumor Inflammation

by Michael C. Schmid, Judith A. Varner
Published 2010-01-01

PI3-kinase γ promotes Rap1a-mediated activation of myeloid cell integrin α4β1, leading to tumor inflammation and growth.

by Michael C Schmid, Irene Franco, Sang Won Kang, Emilio Hirsch, Lawrence A Quilliam, Judith A Varner
Published 2013-01-01

The primacy of β1 integrin activation in the metastatic cascade.

by Hisashi Kato, Zhongji Liao, John V Mitsios, Huan-You Wang, Elena I Deryugina, Judith A Varner, James P Quigley, Sanford J Shattil
Published 2012-01-01

Integrin α4 Enhances Metastasis and May Be Associated with Poor Prognosis in MYCN-low Neuroblastoma.

by Shanique A Young, Katelyn E McCabe, Alena Bartakova, Joe Delaney, Donald P Pizzo, Robert O Newbury, Judith A Varner, David D Schlaepfer, Dwayne G Stupack
Published 2015-01-01

Integrin CD11b activation drives anti-tumor innate immunity

by Michael C. Schmid, Samia Q. Khan, Megan M. Kaneda, Paulina Pathria, Ryan Shepard, Tiani L. Louis, Sudarshan Anand, Gyunghwi Woo, Chris Leem, M. Hafeez Faridi, Terese Geraghty, Anugraha Rajagopalan, Seema Gupta, Mansoor Ahmed, Roberto I. Vazquez-Padron, David A. Cheresh, Vineet Gupta, Judith A. Varner
Published 2018-12-01