Redox Status and Bioenergetics Liaison in Cancer and Neurodegeneration

by Giuseppe Filomeni, Juan P. Bolaños, Pier Giorgio Mastroberardino
Published 2012-01-01

Uncertainties in pentose-phosphate pathway flux assessment underestimate its contribution to neuronal glucose consumption: relevance for neurodegeneration and aging

by Anne-Karine eBouzier-Sore, Juan P Bolanos
Published 2015-05-01

Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

by Rubén Quintana-Cabrera, Israel Manjarrés-Raza, Carlos Vicente-Gutiérrez, Mauro Corrado, Juan P. Bolaños, Luca Scorrano
Published 2021-05-01

Preconditioning-Activated AKT Controls Neuronal Tolerance to Ischemia through the MDM2–p53 Pathway

by Emilia Barrio, Rebeca Vecino, Irene Sánchez-Morán, Cristina Rodríguez, Alberto Suárez-Pindado, Juan P. Bolaños, Angeles Almeida, Maria Delgado-Esteban
Published 2021-07-01

Abrogating mitochondrial ROS in neurons or astrocytes reveals cell-specific impact on mouse behaviour

by Carlos Vicente-Gutierrez, Nicolo Bonora, Daniel Jimenez-Blasco, Irene Lopez-Fabuel, Georgina Bates, Michael P. Murphy, Angeles Almeida, Juan P. Bolaños
Published 2021-05-01

Hippocampal neurons require a large pool of glutathione to sustain dendrite integrity and cognitive function

by Seila Fernandez-Fernandez, Veronica Bobo-Jimenez, Raquel Requejo-Aguilar, Silvia Gonzalez-Fernandez, Monica Resch, Monica Carabias-Carrasco, Joaquim Ros, Angeles Almeida, Juan P. Bolaños
Published 2018-10-01

Targeting PFKFB3 alleviates cerebral ischemia-reperfusion injury in mice

by Olga Burmistrova, Ana Olias-Arjona, Rebeca Lapresa, Daniel Jimenez-Blasco, Tatiana Eremeeva, Dmitry Shishov, Sergei Romanov, Kristina Zakurdaeva, Angeles Almeida, Peter O. Fedichev, Juan P. Bolaños
Published 2019-08-01

Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells

by Maria J. Bueno, Veronica Jimenez-Renard, Sara Samino, Jordi Capellades, Alejandra Junza, María Luz López-Rodríguez, Javier Garcia-Carceles, Irene Lopez-Fabuel, Juan P. Bolaños, Navdeep S. Chandel, Oscar Yanes, Ramon Colomer, Miguel Quintela-Fandino
Published 2019-11-01

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming

by Kate E. Hawkins, Shona Joy, Juliette M.K.M. Delhove, Vassilios N. Kotiadis, Emilio Fernandez, Lorna M. Fitzpatrick, James R. Whiteford, Peter J. King, Juan P. Bolanos, Michael R. Duchen, Simon N. Waddington, Tristan R. McKay
Published 2016-03-01

Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype

by Chiara Soldati, Irene Lopez‐Fabuel, Luca G Wanderlingh, Marina Garcia‐Macia, Jlenia Monfregola, Alessandra Esposito, Gennaro Napolitano, Marta Guevara‐Ferrer, Anna Scotto Rosato, Einar K Krogsaeter, Dominik Paquet, Christian M Grimm, Sandro Montefusco, Thomas Braulke, Stephan Storch, Sara E Mole, Maria A De Matteis, Andrea Ballabio, Julio L Sampaio, Tristan McKay, Ludger Johannes, Juan P Bolaños, Diego L Medina
Published 2021-10-01