Increased motor neuron resilience by small molecule compounds that regulate IGF-II expression

by Teresia M. Osborn, Jonathan Beagan, Ole Isacson
Published 2018-02-01

A Nurr1 agonist causes neuroprotection in a Parkinson's disease lesion model primed with the toll-like receptor 3 dsRNA inflammatory stimulant poly(I:C).

by Gaynor A Smith, Emily M Rocha, Thomas Rooney, Pascal Barneoud, Jesse R McLean, Jonathan Beagan, Teresia Osborn, Madeleine Coimbra, Yongyi Luo, Penelope J Hallett, Ole Isacson
Published 2015-01-01

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons

by Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A. Hayes, Jonathan Beagan, Jesse R. McLean, Sarah C. Izen, Eduardo Perez-Torres, Penelope J. Hallett, Ole Isacson
Published 2015-10-01