Membrane orientation and binding determinants of G protein-coupled receptor kinase 5 as assessed by combined vibrational spectroscopic studies.

by Pei Yang, Alisa Glukhova, John J G Tesmer, Zhan Chen
Published 2013-01-01

Structural and biochemical characterization of the pleckstrin homology domain of the RhoGEF P-Rex2 and its regulation by PIP3

by Jennifer N. Cash, Prateek V. Sharma, John J.G. Tesmer
Published 2019-01-01

Identification and Characterization of Amlexanox as a G Protein-Coupled Receptor Kinase 5 Inhibitor

by Kristoff T. Homan, Emily Wu, Alessandro Cannavo, Walter J. Koch, John J. G. Tesmer
Published 2014-10-01

Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis

by Vania Hinkovska-Galcheva, Taylour Treadwell, Jonathan M. Shillingford, Angela Lee, Akira Abe, John J.G. Tesmer, James A. Shayman
Published 2021-01-01

Determinants of pH profile and acyl chain selectivity in lysosomal phospholipase A2 [S]

by Vania Hinkovska-Galcheva, Robert Kelly, Kelly A. Manthei, Renee Bouley, Wenmin Yuan, Anna Schwendeman, JohnJ.G. Tesmer, James A. Shayman
Published 2018-01-01

The Open Question of How GPCRs Interact with GPCR Kinases (GRKs)

by M. Claire Cato, Yu-Chen Yen, Charnelle J. Francis, Kaely E. Elkins, Afzaal Shareef, Rachel Sterne-Marr, John J. G. Tesmer
Published 2021-03-01

Dissecting G_q/11-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

by Kira Vanessa Blankenbach, Ralf Frederik Claas, Natalie Judith Aster, Anna Katharina Spohner, Sandra Trautmann, Nerea Ferreirós, Justin L. Black, John J. G. Tesmer, Stefan Offermanns, Thomas Wieland, Dagmar Meyer zu Heringdorf
Published 2020-09-01