Olfactory proteotyping: towards the enlightenment of the neurodegeneration

by Joaquín Fernández-Irigoyen, Enrique Santamaría
Published 2019-01-01

Proteomics Insights Into the Molecular Basis of SARS-CoV-2 Infection: What We Can Learn From the Human Olfactory Axis

by Mercedes Lachén-Montes, Mercedes Lachén-Montes, Mercedes Lachén-Montes, Fernando J. Corrales, Fernando J. Corrales, Joaquín Fernández-Irigoyen, Joaquín Fernández-Irigoyen, Joaquín Fernández-Irigoyen, Enrique Santamaría, Enrique Santamaría, Enrique Santamaría
Published 2020-09-01

Alteration in the Cerebrospinal Fluid Lipidome in Parkinson’s Disease: A Post-Mortem Pilot Study

by Joaquín Fernández-Irigoyen, Paz Cartas-Cejudo, Marta Iruarrizaga-Lejarreta, Enrique Santamaría
Published 2021-04-01

Olfactory Bulb Proteomics Reveals Widespread Proteostatic Disturbances in Mixed Dementia and Guides for Potential Serum Biomarkers to Discriminate Alzheimer Disease and Mixed Demen...

by Mercedes Lachén-Montes, Ignacio Íñigo-Marco, Paz Cartas-Cejudo, Joaquín Fernández-Irigoyen, Enrique Santamaría
Published 2021-06-01

Proteomic Characterization of the Olfactory Molecular Imbalance in Dementia with Lewy Bodies

by Mercedes Lachén-Montes, Naroa Mendizuri, Domitille Schvartz, Joaquín Fernández-Irigoyen, Jean Charles Sánchez, Enrique Santamaría
Published 2020-09-01

Influence of short‐term training on functional capacity and (anti‐)inflammatory immune signalling in acute hospitalization

by Robinson Ramírez‐Vélez, Nicolás Martínez‐Velilla, Joaquín Fernández‐Irigoyen, Enrique Santamaría, Sara Palomino‐Echeverría, Mikel Izquierdo
Published 2020-08-01

Early-Onset Molecular Derangements in the Olfactory Bulb of Tg2576 Mice: Novel Insights Into the Stress-Responsive Olfactory Kinase Dynamics in Alzheimer’s Disease

by Mercedes Lachen-Montes, Mercedes Lachen-Montes, Mercedes Lachen-Montes, Andrea González-Morales, Andrea González-Morales, Andrea González-Morales, Maialen Palomino, Karina Ausin, Karina Ausin, Marta Gómez-Ochoa, María Victoria Zelaya, María Victoria Zelaya, María Victoria Zelaya, Isidro Ferrer, Alberto Pérez-Mediavilla, Alberto Pérez-Mediavilla, Joaquín Fernández-Irigoyen, Joaquín Fernández-Irigoyen, Joaquín Fernández-Irigoyen, Enrique Santamaría, Enrique Santamaría, Enrique Santamaría
Published 2019-06-01

Amyotrophic Lateral Sclerosis Is Accompanied by Protein Derangements in the Olfactory Bulb-Tract Axis

by Mercedes Lachén-Montes, Naroa Mendizuri, Karina Ausin, Pol Andrés-Benito, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamaría
Published 2020-11-01

Network-Driven Proteogenomics Unveils an Aging-Related Imbalance in the Olfactory IκBα-NFκB p65 Complex Functionality in Tg2576 Alzheimer’s Disease Mouse Model

by Maialen Palomino-Alonso, Mercedes Lachén-Montes, Andrea González-Morales, Karina Ausín, Alberto Pérez-Mediavilla, Joaquín Fernández-Irigoyen, Enrique Santamaría
Published 2017-10-01

Olfactory bulb neuroproteomics reveals a chronological perturbation of survival routes and a disruption of prohibitin complex during Alzheimer’s disease progression

by Mercedes Lachén-Montes, Andrea González-Morales, María Victoria Zelaya, Estela Pérez-Valderrama, Karina Ausín, Isidro Ferrer, Joaquín Fernández-Irigoyen, Enrique Santamaría
Published 2017-08-01

Neuroanatomical Quantitative Proteomics Reveals Common Pathogenic Biological Routes between Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

by Marina Oaia Iridoy, Irene Zubiri, María Victoria Zelaya, Leyre Martinez, Karina Ausín, Mercedes Lachen-Montes, Enrique Santamaría, Joaquín Fernandez-Irigoyen, Ivonne Jericó
Published 2018-12-01

N-terminal acetylation mutants affect alpha-synuclein stability, protein levels and neuronal toxicity

by Rodrigo Vinueza-Gavilanes, Ignacio Íñigo-Marco, Laura Larrea, Marta Lasa, Beatriz Carte, Enrique Santamaría, Joaquín Fernández-Irigoyen, Ricardo Bugallo, Tomás Aragón, Rafael Aldabe, Montserrat Arrasate
Published 2020-04-01

Cannabis Use Induces Distinctive Proteomic Alterations in Olfactory Neuroepithelial Cells of Schizophrenia Patients

by Marta Barrera-Conde, Karina Ausin, Mercedes Lachén-Montes, Joaquín Fernández-Irigoyen, Liliana Galindo, Aida Cuenca-Royo, Cristina Fernández-Avilés, Víctor Pérez, Rafael de la Torre, Enrique Santamaría, Patricia Robledo
Published 2021-02-01

Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein 12

by Jaime Ibarrola, Rafael Sadaba, Ernesto Martinez-Martinez, Amaia Garcia-Peña, Vanessa Arrieta, Virginia Alvarez, Amaya Fernández-Celis, Alicia Gainza, Victoria Cachofeiro, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Frederic Jaisser, Natalia Lopez-Andres
Published 2018-05-01

Fiber-based early diagnosis of venous thromboembolic disease by label-free D-dimer detection

by Pablo Zubiate, Aitor Urrutia, Carlos R. Zamarreño, Josune Egea-Urra, Joaquín Fernández-Irigoyen, Ambra Giannetti, Francesco Baldini, Silvia Díaz, Ignacio R. Matias, Francisco J. Arregui, Enrique Santamaría, Francesco Chiavaioli, Ignacio Del Villar
Published 2019-10-01

Absence of Nuclear p16 Is a Diagnostic and Independent Prognostic Biomarker in Squamous Cell Carcinoma of the Cervix

by Saioa Mendaza, Joaquín Fernández-Irigoyen, Enrique Santamaría, Tamara Zudaire, Rosa Guarch, David Guerrero-Setas, August Vidal, José Santos-Salas, Xavier Matias-Guiu, Karina Ausín, María José Díaz de Cerio, Esperanza Martín-Sánchez
Published 2020-03-01

Increased C-X-C Motif Chemokine Ligand 12 Levels in Cerebrospinal Fluid as a Candidate Biomarker in Sporadic Amyotrophic Lateral Sclerosis

by Pol Andrés-Benito, Mònica Povedano, Raúl Domínguez, Carla Marco, Maria J. Colomina, Óscar López-Pérez, Isabel Santana, Inês Baldeiras, Sergio Martínez-Yelámos, Inga Zerr, Franc Llorens, Joaquín Fernández-Irigoyen, Enrique Santamaría, Isidro Ferrer
Published 2020-11-01

Profound Reprogramming towards Stemness in Pancreatic Cancer Cells as Adaptation to AKT Inhibition

by Hugo Arasanz, Carlos Hernández, Ana Bocanegra, Luisa Chocarro, Miren Zuazo, Maria Gato, Karina Ausin, Enrique Santamaría, Joaquín Fernández-Irigoyen, Gonzalo Fernandez, Eva Santamaria, Carlos Rodríguez, Idoia Blanco-Luquin, Ruth Vera, David Escors, Grazyna Kochan
Published 2020-08-01

Understanding the Molecular Mechanism of miR-877-3p Could Provide Potential Biomarkers and Therapeutic Targets in Squamous Cell Carcinoma of the Cervix

by Saioa Mendaza, Joaquín Fernández-Irigoyen, Enrique Santamaría, Imanol Arozarena, David Guerrero-Setas, Tamara Zudaire, Rosa Guarch, August Vidal, José-Santos Salas, Xavier Matias-Guiu, Karina Ausín, Carmen Gil, Rubén Hernández-Alcoceba, Esperanza Martín-Sánchez
Published 2021-04-01

Soluble St2 Induces Cardiac Fibroblast Activation and Collagen Synthesis via Neuropilin-1

by Lara Matilla, Vanessa Arrieta, Eva Jover, Amaia Garcia-Peña, Ernesto Martinez-Martinez, Rafael Sadaba, Virginia Alvarez, Adela Navarro, Amaya Fernandez-Celis, Alicia Gainza, Enrique Santamaria, Joaquín Fernandez-Irigoyen, Patrick Rossignol, Faiez Zannad, Natalia Lopez-Andres
Published 2020-07-01