A Targeted-Covalent Inhibitor of 17β-HSD1 Blocks Two Estrogen-Biosynthesis Pathways: In Vitro (Metabolism) and In Vivo (Xenograft) Studies in T-47D Breast Cancer Models

by Donald Poirier, Jenny Roy, René Maltais
Published 2021-04-01

Synthesis, NMR Characterization, and Antileukemic Activity of <i>N</i>-Nonanoylpiperazinyl-5α-Androstane-3α,17β-Diol A-Ring Derivatives

by Donald Poirier, Imad Raad, Jenny Roy, René Maltais
Published 2021-12-01

Synthesis of 5&amp;#945;-Androstane-17-spiro-&amp;#948;-lactones with a 3-Keto, 3-Hydroxy, 3-Spirocarbamate or 3-Spiromorpholinone as Inhibitors of 17&amp;#946;-Hydroxysteroid Dehy...

by Donald Poirier, Jenny Roy, Béatrice Tchédam Ngatcha, Guy Bertrand Djigoué
Published 2013-01-01

SUBSTITUTED 1,3-PHENYL(PYRIDYL) PROPENONES AND DERIVATIVES WITH THIOSEMICARBAZIDIC GROUPS. STRUCTRURE – (HL-60) ANTILEUKEMIA ACTIVITY RELATIONSHIP

by Ana Popusoi, Nicanor Barba, Aurelian Gulea, Jenny Roy, Donald Poirier
Published 2014-12-01

The Aminosteroid Derivative RM-133 Shows In Vitro and In Vivo Antitumor Activity in Human Ovarian and Pancreatic Cancers.

by Lucie Carolle Kenmogne, Diana Ayan, Jenny Roy, René Maltais, Donald Poirier
Published 2015-01-01

Investigation of the In Vitro and In Vivo efficiency of RM-532-105, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, in LAPC-4 prostate cancer cell and tumor models.

by Lucie Carolle Kenmogne, Jenny Roy, René Maltais, Mélanie Rouleau, Bertrand Neveu, Frédéric Pouliot, Donald Poirier
Published 2017-01-01